ENSMUSG00000006546


Mus musculus

Features
Gene ID: ENSMUSG00000006546
  
Biological name :Cryba2
  
Synonyms : Beta-crystallin A2 / Cryba2 / Q9JJV1
  
Possible biological names infered from orthology : crystallin beta A2 / P53672
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C4
Gene start: 74889934
Gene end: 74893143
  
Corresponding Affymetrix probe sets: 10355662 (MoGene1.0st)   1419011_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140298
Ensembl peptide - ENSMUSP00000006721
NCBI entrez gene - 12958     See in Manteia.
MGI - MGI:104336
RefSeq - NM_021541
RefSeq - XM_006495656
RefSeq Peptide - NP_067516
swissprot - A0A087WQQ2
swissprot - Q9JJV1
Ensembl - ENSMUSG00000006546
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cryba2aENSDARG00000030349Danio rerio
 cryba2bENSDARG00000041925Danio rerio
 CRYBA2ENSGALG00000011354Gallus gallus
 CRYBA2ENSG00000163499Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cryba1 / beta-crystallin A1 isoform 2 / P05813* / crystallin beta A1*ENSMUSG0000000072453
Cryba4 / Q9JJV0 / Beta-crystallin A4 / P53673* / crystallin beta A4*ENSMUSG0000006697553
Crybb1 / Q9WVJ5 / Beta-crystallin B1 Beta-crystallin B1B / P53674* / crystallin beta B1*ENSMUSG0000002934344
Crybb3 / Q9JJU9 / Mus musculus crystallin, beta B3 (Crybb3), transcript variant 8, mRNA. / P26998* / crystallin beta B3*ENSMUSG0000002935244
Crygn / Q8VHL5 / Gamma-crystallin N / Q8WXF5* / crystallin gamma N*ENSMUSG0000003813540
Crybb2 / P62696 / Beta-crystallin B2 / P43320* / crystallin beta B2*ENSMUSG0000004224038
Crygb / P04344 / Gamma-crystallin B / P07316* / crystallin gamma B*ENSMUSG0000007365833
Crygs / O35486 / Beta-crystallin S / P22914* / crystallin gamma S*ENSMUSG0000003350132
Crygd / P04342 / Gamma-crystallin D / P07320* / crystallin gamma D*ENSMUSG0000006729932
Crygf / Q9CXV3 / Gamma-crystallin F / CRYGD* / P07320* / crystallin gamma D*ENSMUSG0000002594531
Crygc / Q61597 / Gamma-crystallin C / P07315* / crystallin gamma C*ENSMUSG0000002595231
Cryge / Q03740 / Gamma-crystallin E / CRYGD* / P07320* / crystallin gamma D*ENSMUSG0000007087031
Cryga / P04345 / Gamma-crystallin A / P11844* / crystallin gamma A*ENSMUSG0000004442930


Protein motifs (from Interpro)
Interpro ID Name
 IPR001064  Beta/gamma crystallin
 IPR011024  Gamma-crystallin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002088 lens development in camera-type eye IMP
 molecular_functionGO:0005212 structural constituent of eye lens TAS
 molecular_functionGO:0042803 protein homodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001306 small lens "reduced size of the transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Otop1tm1Dor/Otop1tm1Dor
Genetic Background: Not Specified

Allelic Composition: Cryba2Aca30/Cryba2Aca30
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

 MP:0001312 abnormal cornea morphology "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Otop1tm1Dor/Otop1tm1Dor
Genetic Background: Not Specified

 MP:0010251 subcapsular cataracts "a lens opacity localized beneath the anterior or posterior lens capsule" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: Otop1tm1Dor/Otop1tm1Dor
Genetic Background: Not Specified

 MP:0010263 total cataracts "a lens opacity which involves both nuclear and cortical regions, including all fibers of a lens; usually congenital" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: Cryba2Aca30/Cryba2Aca30
Genetic Background: involves: C3HeB/FeJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr