| MP:0000018 | small ears | "outer ears of a smaller than normal size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
|
| MP:0000023 | abnormal ear distance/ position | "anomaly in the space between or the placement of the outer ears " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: 129S6.129-Chrdtm1Emdr
|
| MP:0000030 | abnormal tympanic ring morphology | "malformed bony ring at the ear canal to which the tympanic membrane is attached" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
|
| MP:0000049 | abnormal middle ear morphology | "malformation or malfunction of any components of the tympanic cavity or its ossicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
|
| MP:0000087 | absent mandible | "missing the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cdkn2dtm1Maro/Cdkn2dtm1Maro
Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: 129S6.129-Chrdtm1Emdr
|
| MP:0000088 | short mandible | "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk Chrdtm1Emdr
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: 129S6.129-Chrdtm1Emdr
|
| MP:0000111 | cleft palate | "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
Show
Allelic Composition: Adipoqtm1Chan/Adipoqtm1Chan
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: 129S6.129-Chrdtm1Emdr
|
| MP:0000276 | right ventricle hypertrophy | "increased size of the right ventricle" [J:33629] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0000433 | microcephaly | "an abnormally small head" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
|
| MP:0000458 | abnormal mandible morphology | "malformation of the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Twsg1tm1.1Mboc/Twsg1tm1.1Mboc
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N
|
| MP:0000680 | absent parathyroid glands | "missing the two small, paired endocrine glands, usually found embedded in the connective tissue capsule on the posterior surface of the thyroid gland, which secrete parathyroid hormone (PTH) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
|
| MP:0000681 | abnormal thyroid gland morphology | "anomalous structure of the endocrine gland located in the front and to the sides of the upper part of the trachea and which secretes thyroid hormone and calcitonin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
|
| MP:0000705 | athymia | "absence of the primary lymphoid organ" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk Chrdtm1Emdr
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: 129S6.129-Chrdtm1Emdr
|
| MP:0000787 | abnormal telencephalon morphology | "any malformation or absence of the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Cdkn2dtm1Maro/Cdkn2dtm1Maro
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0000830 | abnormal diencephalon morphology | "any malformation or absence of the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
Show
Allelic Composition: Cdkn2dtm1Maro/Cdkn2dtm1Maro
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0000913 | abnormal brain development | "malformed or incomplete differentiation of the brain" [MGI:cls, J:49840] |
Show
Allelic Composition: Uqcrfs1tm1Ctm/Uqcrfs1+
Genetic Background: Not Specified
|
| MP:0000932 | absent notochord | "missing axial fibrocellular cord in embryos around which develops the vertebral primordia" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:12622] |
Show
Allelic Composition: Cdkn2dtm1Maro/Cdkn2dtm1Maro
Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0001081 | abnormal cranial ganglia morphology | "any anomaly, deformity, or malformation of the groups of nerve cell bodies associated with the twelve cranial nerves" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:45302] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0001083 | small geniculate ganglion | "reduced size of the geniculate ganglion or decreased size of sensory neuron cell bodies associated with the facial nerve" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0001085 | small petrosal ganglion | "reduced size of the petrosal ganglion" [J:25565] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0001086 | absent petrosal ganglion | " missing the group of sensory neuron cell bodies comprising the petrosal ganglion" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:45302] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0001088 | small nodose ganglion | "reduced size of the nodose ganglion" [J:25565, J:17123] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0001089 | absent nodose ganglion | "missing the group of sensory neurons comprising the nodose ganglion" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:45302] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0001092 | abnormal trigeminal ganglion morphology | "malformed group of sensory neuron cell bodies associated with the trigeminal nerve (fifth cranial nerve)" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33038] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
|
| MP:0001293 | anophthalmia | "congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979] |
Show
Allelic Composition: Cdkn2dtm1Maro/Cdkn2dtm1Maro
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0001399 | hyperactivity | "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125] |
Show
Allelic Composition: Uqcrfs1tm1Ctm/Uqcrfs1+
Genetic Background: Not Specified
|
| MP:0001417 | decreased exploration in new environment | "less amount of time spent investigating a new location" [J:79870] |
Show
Allelic Composition: Uqcrfs1tm1Ctm/Uqcrfs1+
Genetic Background: Not Specified
|
| MP:0001463 | abnormal spatial learning | "defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University] |
Show
Allelic Composition: Uqcrfs1tm1Ctm/Uqcrfs1+
Genetic Background: Not Specified
|
| MP:0001575 | cyanosis | "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0001680 | abnormal mesoderm development | "failure or abnormality in the formation of the mesoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
|
| MP:0001683 | absent mesoderm | "missing or failure to differentiate the middle primary germ layer " [J:40594] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0001706 | abnormal left-right axis patterning | "anomaly in the formation or development of the body or a specific organ of the body in relation to the left and right sides of the body or organ" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Cdkn2dtm1Maro/Cdkn2dtm1Maro
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0001914 | hemorrhage | "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0002081 | perinatal lethality | "death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Twsg1tm1.1Mboc/Twsg1tm1.1Mboc
Genetic Background: B6.129S7-Twsg1tm1.1Mboc
|
| MP:0002085 | abnormal embryonic tissue morphology | "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nodaltm1Rob/Nodal+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
|
| MP:0002086 | abnormal extraembryonic tissue morphology | "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:40594, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
|
| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Casp8tm1.1Raz/Casp8tm1.1Raz
Genetic Background: involves: 129P2/OlaHsd
|
| MP:0002177 | abnormal outer ear morphology | "malformation or malfunction of any components of the auricles or external acoustic meatus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk Chrdtm1Emdr
|
| MP:0002191 | abnormal artery morphology | "malformation of the blood vessels that carry blood away from the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
|
| MP:0002192 | hydrops fetalis | "an abnormal accumulation of serous fluid in fetal tissues" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
|
| MP:0002252 | abnormal oropharynx morphology | "structural anomaly of the portion of the pharynx that lies between the soft palate and the upper edge of the epiglottis" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
|
| MP:0002256 | abnormal laryngeal cartilage morphology | "any structural anomaly of the cartilagenous structures that support the larynx" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
Show
Allelic Composition: Gli1tm2Alj/Gli1tm2Alj,Gli2tm1Alj/Gli2+
Genetic Background: involves: 129/Sv * Black Swiss * Swiss Webster
|
| MP:0002258 | abnormal cricoid cartilage morphology | "any structural anomaly of the most inferior of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0002260 | abnormal thyroid cartilage morphology | "any structural anomaly of the largest of the laryngeal cartilages " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0002633 | persistent truncus arteriosis | "complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Tbx1m1Jlk/Tbx1m1Jlk
Genetic Background: 129/Sv-Tbx1m1Jlk Chrdtm1Emdr
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: 129S6.129-Chrdtm1Emdr
|
| MP:0002672 | abnormal branchial arch artery morphology | "malformation of the vessels formed within the five pairs of branchial arches in embryogenesis; in the adult, some of these vessels give rise to the great vessels" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: 129S6.129-Chrdtm1Emdr
|
| MP:0002884 | abnormal branchial arches | "malformation or anomaly in the transient structures of the embryo that develop into regions of the head, neck and ears" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lmx1adr-kjmi/Lmx1adr-kjmi
Genetic Background: involves: 129 * C57BL/6J
|
| MP:0002919 | enhanced paired-pulse facilitation | "increase in the response of central synapses when activated twice in rapid succession; indicative of defects in short-term plasticity due to greater increase of neurotransmitter release at the second stimulus" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
Show
Allelic Composition: Uqcrfs1tm1Ctm/Uqcrfs1+
Genetic Background: Not Specified
|
| MP:0002925 | abnormal cardiovascular development | "aberrant formation or incomplete differentiation of the cardiovascular system" [RGD:Rat Genome Database submission] |
Show
Allelic Composition: Lmx1adr-kjmi/Lmx1adr-kjmi
Genetic Background: involves: 129 * C57BL/6J
|
| MP:0002950 | abnormal neural crest cell migration | "defect in the dispersion of the transient and migratory group of cells that emerge from the dorsal region of the neural tube and migrate to many peripheral locations to form various tissues of the adult" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0003008 | enhanced long term potentiation | "greater than the normal persistent robust synaptic response induced by synchronous stimulation of pre- and postsynaptic cells " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3, J:81922] |
Show
Allelic Composition: Uqcrfs1tm1Ctm/Uqcrfs1+
Genetic Background: Not Specified
|
| MP:0003047 | abnormal thoracic vertebrae morphology | "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0003232 | abnormal forebrain development | "anomaly in the formation or patterning of the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [J:93081, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cdkn2dtm1Maro/Cdkn2dtm1Maro
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0003321 | tracheoesophageal fistula | "an abnormal passage between the esophagus and the trachea, acquired or congenital, often associated with esophageal atresia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
Show
Allelic Composition: Cdkn2dtm1Maro/Cdkn2dtm1Maro
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0003345 | decreased number of ribs | "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
Show
Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr,Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: involves: 129 * C57BL/6 * SJL
|
| MP:0003461 | abnormal response to novel object | "altered investigative behavior from controls in reactions associated with exposing an animal to a novel object" [CFG:Center for Functional Genomics, Northwestern University] |
Show
Allelic Composition: Uqcrfs1tm1Ctm/Uqcrfs1+
Genetic Background: Not Specified
|
| MP:0003499 | thyroid hypoplasia | |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0003703 | abnormal vestibulocochlear ganglion morphology | "malformed group of neuron cell bodies associated with the eighth cranial nerve during embryogenesis; splits in later development to form the cochlear and vestibular ganglia" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0003743 | abnormal facial morphology | "anomalous structure or development of the face" [ncbi:Matthew Mailman, NCBI request] |
Show
Allelic Composition: Cdkn2dtm1Maro/Cdkn2dtm1Maro
Genetic Background: involves: 129X1/SvJ * C57BL/6
|
| MP:0003874 | absent branchial arches | "missing the transient structures of the embryo that develop into regions of the head, neck and ears" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
|
| MP:0003938 | abnormal ear development | "developmental anomaly of any of the structures involved in the ear or vestibular system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Lmx1adr-kjmi/Lmx1adr-kjmi
Genetic Background: involves: 129 * C57BL/6J
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: 129S6.129-Chrdtm1Emdr
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| MP:0004113 | abnormal aortic arch morphology | "structural anomoly of the portion of the descending aorta proceeding from the arch of the aorta and extending to the diaphragm " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004158 | right aortic arch | "the aortic arch lies to the right of the trachea and esophagus; results from persistance of the entire right dorsal arch and involution of a segment of the left arch" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004160 | retroesophageal right subclavian artery | "the subclavian artery aberrantly originates from the aortic arch distal to the origin of the left subclavian artery, i.e., it is the last branch of the aortic arch" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004252 | abnormal direction of looping morphogenesis | "deviation from the normal rightward direction of cardiac looping" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pax63Neu/Pax63Neu
Genetic Background: either: (involves: 102 * C3H) or (involves: C3H)
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nogtm1Amc/Nogtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nodaltm1Rob/Nodal+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
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| MP:0004310 | small otic vesicle | "reduced size of the simple epithelial sac formed from the otic placode that gives rise to the structures of the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004387 | abnormal prechordal plate morphology | "any structural anomaly of the horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann s organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nodaltm1Rob/Nodal+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
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| MP:0004422 | small temporal bone | "reduced size of the large, irregular bone located at the base and side of the skull" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004450 | presphenoid bone hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the anterior part of the body of the sphenoid bone in front of the basisphenoid; it is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004541 | absent auditory tube | "absence of the tube connecting the tympanic cavity and the nasopharynx" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004544 | absent esophagus | "absence of the part of the digestive canal through which food passes from the pharynx to the stomach" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004549 | small trachea | "reduced size of the tube descending from the larynx and branching into the right and left main bronchi" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004554 | small pharynx | "reduced size/diameter of the passage between the mouth and the posterior nares and the larynx and esophagus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nogtm1Amc/Nogtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004556 | enlarged allantois | "increased size of the fetal membrane which contributes to the formation of the umbilical cord and placental blood vessels" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004572 | fusion of basioccipital and basisphenoid bone | "union of the basioccipital and basisphenoid bones into one structure, when this fusion does not normally occur (such as in a species where these bones normally persist as separate entities)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004592 | small mandible | "reduced size of the lower bony framework of the mouth where the inferior teeth are held" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004599 | abnormal vertebral arch morphology | "any structural anomaly of the dorsal part of a vertebra, consisting of a pair of pedicles, a pair of laminae, and seven processes (four articular processes, two transverse processes, and one spinous process)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr,Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: involves: 129 * C57BL/6 * SJL
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Twsg1tm1.1Mboc/Twsg1tm1.1Mboc
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N
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| MP:0004618 | thoracic vertebral transformation | "homeotic transformation of any thoracic vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr,Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: involves: 129 * C57BL/6 * SJL
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| MP:0004670 | small vertebral body | "decreased size of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004753 | abnormal miniature excitatory postsynaptic currents | "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an excitatory impulse" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Uqcrfs1tm1Ctm/Uqcrfs1+
Genetic Background: Not Specified
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| MP:0004899 | absent squamosal bone | "absence of the thin, plate-like part of the temporal bone" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004911 | absent mandibular condyloid process | "absence of the round bump of bone and constricted neck portion that arises from the upper surface of the mandibular ramus (perpendicular portion) and articulates with the articular disk of the temporomandibular joint" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004912 | absent mandibular coronoid process | "absence of the thin, flattened, triangular eminence that arises from the upper surface of the mandibular ramus (perpendicular portion)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0004913 | absent mandibular angle | "absence of the portion of the mandible where the body of the mandible (horizontal portion) and the rami (perpendicular portions) meet; these normally unite nearly at right angles" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0005157 | holoprosencephaly | "presence of a single forebrain hemisphere or lobe; often accompanied by a deficit in median facial development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83058] |
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Allelic Composition: Cdkn2dtm1Maro/Cdkn2dtm1Maro
Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nodaltm1Rob/Nodal+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
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| MP:0005163 | cyclopia | "a congenital defect in which the two orbits are united to form a single cavity containing one eye" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60303] |
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Allelic Composition: Cdkn2dtm1Maro/Cdkn2dtm1Maro
Genetic Background: involves: 129X1/SvJ * C57BL/6
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| MP:0005226 | abnormal vertebral arch development | "anomalous formation of the posterior projection from the body of a vertebra that encloses the vertebral foramen " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0005508 | abnormal skeleton morphology | "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Bmpertm1Emdr/Bmpertm1Emdr,Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: involves: 129 * C57BL/6 * SJL
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| MP:0005590 | increased vasodilation | "greater than the expected or normal widening of the lumen of the blood vessels" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0005657 | abnormal neural plate morphology | "malformation or absence of the neuroectodermal area of the embryo s dorsal surface that develops into the neural tube and neural crest" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator, J:68142] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0006020 | reduced size of tympanic ring | "smaller than average tympanic ring" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0006031 | abnormal branchial pouch morphology | "malfomation or anomaly in the series of grooves that form between the branchial arches; these endodermal evaginations develop into epithelial tissues and organs" [smb:Susan M Bello, Mouse Genome Informatics Curator, Gray s Anatomy:ISBN 0-914294-08-3] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0006285 | absent inner ear | "absence of all components of the labyrinth, including the semicircular canals, vestibule and cochlea" [J:86619, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0006288 | small otic capsule | "reduced size of the cartilage or bony capsule surrounding the inner ear mechanism" [J:59285, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0006290 | proboscis | "a long, cylindric protuberance of the face that, in cyclopia or ethmocephaly, represents the nose" [J:92058, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nogtm1Amc/Nogtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
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| MP:0006291 | aprosencephaly | "the most severe form of holoprosencephaly where the entire prosencephalon (both telencephalon and diencephalon) fails to develop while the hindbrain is largely preserved" [J:60303, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nogtm1Amc/Nogtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
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| MP:0006293 | absent olfactory placodes | "absence of the paired ectodermal placodes that come to lie in the bottom of the olfactory pits as the pits are deepened by the growth of the surrounding medial and lateral nasal processes " [J:71787, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nogtm1Amc/Nogtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
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| MP:0006295 | absent sclerotome | "absence of the group of mesenchymal cells that emerge from the ventromedial part of a somite and migrate toward the notochord to give rise to the ribs and vertebrae" [J:60303, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nogtm1Amc/Nogtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
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| MP:0006386 | absent somites | "missing all somites" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0008921 | increased neurotransmitter release | "increased production or release of endogenous signaling molecules normally secreted by neurons that alter the behavior of neurons or effector cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Uqcrfs1tm1Ctm/Uqcrfs1+
Genetic Background: Not Specified
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| MP:0008926 | abnormal anterior definitive endoderm morphology | "any structural anomaly of the mesendoderm which first migrates from the node and which gives rise to the gut" [PMID:12464432] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nodaltm1Rob/Nodal+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
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| MP:0009266 | abnormal mesendoderm development | "failure or abnormality in the formation of the embryonic cell layer that gives rise to both the endoderm and mesoderm" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nogtm1Amc/Nogtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nodaltm1Rob/Nodal+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
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| MP:0009655 | abnormal secondary palate development | "any anomaly in the formation of the part of the palate that is formed during embryonic development when palatal projections from the inner part of the maxillary processes emerge, extend and elevate into a horizontal position above the tongue" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:16942766] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0009888 | palatal shelves fail to meet at midline | "polarized growth towards the midline following palatal shelf elevation does not occur" [PMID:16942766] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0009890 | cleft secondary palate | "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0009899 | hyoid bone hypoplasia | "underdevelopment of the hyoid bone, usually due to a deficiency in the number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0010335 | fused first branchial arch | "the first arch fails to fully divide along the midline" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nodaltm1Rob/Nodal+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
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| MP:0010657 | absent pulmonary trunk | "absence of the region of the pulmonary artery that arises from the right ventricle to the division of the right and left pulmonary artery" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0010663 | abnormal brachiocephalic trunk morphology | "any structural anomaly of the short first aortic arch branch and divides into the right subclavian artery and the right common carotid artery" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0010729 | absent arcus anterior | "absence of the arch that connects the lateral masses of the atlas anteriorly and articulates with the anterior articular facet of the dens of the axis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
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| MP:0011090 | partial perinatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Uqcrfs1tm1Ctm/Uqcrfs1+
Genetic Background: Not Specified
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| MP:0011097 | complete embryonic lethality before turning of embryo | "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0011099 | complete lethality throughout fetal growth and development | "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nogtm1Amc/Nogtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
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| MP:0011107 | partial embryonic lethality before turning of embryo | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nogtm1Amc/Nogtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
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| MP:0011108 | partial embryonic lethality during organogenesis | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nogtm1Amc/Nogtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
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| MP:0011109 | partial lethality throughout fetal growth and development | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0011259 | abnormal cephalic neural fold morphology | "any structural anomaly of the elevated margins of the neural groove that are located in the future cephalic region of the embryo" [ISBN:0-683-40008-8, MGI:csmith] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nogtm1Amc/Nogtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
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| MP:0012138 | decreased forebrain size | "size reduction or truncation of the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)" [GO:0048853] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr,Nogtm1Amc/Nogtm1Amc
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J
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| MP:0012729 | abnormal common carotid artery morphology | "any structural anomaly of the left or right common carotid arteries which extend headward on each side of the anterior neck and deliver oxygenated nutrient filled blood from the heart to the head, neck and brain; the left originates in the arch of the aorta over the heart; the right originates in the brachiocephalic trunk, the largest branch from the arch of the aorta; each common carotid artery divides into an external and an internal carotid artery" [MGI:anna] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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| MP:0030375 | short zygomatic arch | "decreased length of the bony arch that, in vertebrates, extends along the side or front of the skull beneath the eye socket and is formed by the temporal process of the zygomatic bone and the zygomatic process of the temporal bone" [MGI:anna] |
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Allelic Composition: Chrdtm1Emdr/Chrdtm1Emdr
Genetic Background: either: B6SJL.129-Chrdtm1Emdr or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J)
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