ENSMUSG00000007739


Mus musculus
proteinCct4bindingfoldingregulationtcp-localizationbodychaperonindomainsuperfamilytelomerasecajalt-complexcomplexgroel-likezonapellucidatelomeremicrotubulecelltriccctconservedsitecpnfamilydeltasubunitchaperonetailless

Features
Gene ID: ENSMUSG00000007739
  
Biological name :Cct4
  
Synonyms : Cct4 / chaperonin containing Tcp1, subunit 4 (delta) / P80315
  
Possible biological names infered from orthology : chaperonin containing TCP1 subunit 4 / P50991
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: A3.2
Gene start: 22990519
Gene end: 23003780
  
Corresponding Affymetrix probe sets: 10374564 (MoGene1.0st)   1415867_at (Mouse Genome 430 2.0 Array)   1415868_at (Mouse Genome 430 2.0 Array)   1430034_at (Mouse Genome 430 2.0 Array)   1433447_x_at (Mouse Genome 430 2.0 Array)   1438560_x_at (Mouse Genome 430 2.0 Array)   1456082_x_at (Mouse Genome 430 2.0 Array)   1456572_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133667
Ensembl peptide - ENSMUSP00000134248
Ensembl peptide - ENSMUSP00000020562
Ensembl peptide - ENSMUSP00000133523
Ensembl peptide - ENSMUSP00000133677
NCBI entrez gene - 12464     See in Manteia.
MGI - MGI:104689
RefSeq - NM_009837
RefSeq Peptide - NP_033967
swissprot - Q564F4
swissprot - G3UXF3
swissprot - G3UXG2
swissprot - G3UYW5
swissprot - G5E839
swissprot - P80315
Ensembl - ENSMUSG00000007739
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cct4ENSDARG00000013475Danio rerio
 CCT4ENSGALG00000008812Gallus gallus
 CCT4ENSG00000115484Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002194  Chaperonin TCP-1, conserved site
 IPR002423  Chaperonin Cpn60/TCP-1 family
 IPR012717  T-complex protein 1, delta subunit
 IPR017998  Chaperone tailless complex polypeptide 1 (TCP-1)
 IPR027409  GroEL-like apical domain superfamily
 IPR027410  TCP-1-like chaperonin intermediate domain superfamily
 IPR027413  GroEL-like equatorial domain superfamily


Gene Ontology (GO)
protein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationprotein foldingcell recognitionnitrogen compound metabolic processbiosynthetic processcellular component organizationcellular metabolic processprimary metabolic processregulation of biological qualityorganic substance metabolic processregulation of molecular functionmacromolecule localizationestablishment of localizationcellular localizationprotein foprotein foldingcell recogcell recognitionnitrogen cnitrogen compound metabolic processbiosynthetbiosynthetic processcellular ccellular component organizationcellular mcellular metabolic processprimary meprimary metabolic processregulationregulation of biological qualityorganic suorganic substance metabolic processregulationregulation of molecular functionmacromolecmacromolecule localizationestablishmestablishment of localizationcellular lcellular localization
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compoorganic cyclic compound bindingheterocyclic compounheterocyclic compound bindingsmall molecule bindismall molecule bindingprotein bindingprotein bindingion bindingion bindingcarbohydrate derivatcarbohydrate derivative bindingdrug bindingdrug binding
protein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexprotein-containing complexcellorganellemembrane-enclosed lumensupramolecular complexprotein-containing complexprotein-containing complexcellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumensupramolecular complexsupramolecular complex
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006458 "de novo" protein folding IBA
 biological_processGO:0007339 binding of sperm to zona pellucida IDA
 biological_processGO:0032212 positive regulation of telomere maintenance via telomerase IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0051973 positive regulation of telomerase activity IEA
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 biological_processGO:0090666 scaRNA localization to Cajal body IEA
 biological_processGO:1901998 toxin transport IMP
 biological_processGO:1904851 positive regulation of establishment of protein localization to telomere IEA
 biological_processGO:1904871 positive regulation of protein localization to Cajal body IEA
 biological_processGO:1904874 positive regulation of telomerase RNA localization to Cajal body IEA
 cellular_componentGO:0002199 zona pellucida receptor complex IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005832 chaperonin-containing T-complex IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0044297 cell body IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IBA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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