ENSMUSG00000009214


Mus musculus

Features
Gene ID: ENSMUSG00000009214
  
Biological name :Mymk
  
Synonyms : Mymk / Protein myomaker / Q9D1N4
  
Possible biological names infered from orthology : A6NI61 / myomaker, myoblast fusion factor
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: A3
Gene start: 27061636
Gene end: 27072179
  
Corresponding Affymetrix probe sets: 10481175 (MoGene1.0st)   1419050_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000009358
Ensembl peptide - ENSMUSP00000128491
NCBI entrez gene - 66139     See in Manteia.
MGI - MGI:1913389
RefSeq - NM_001159602
RefSeq - NM_025376
RefSeq Peptide - NP_001153074
RefSeq Peptide - NP_079652
swissprot - Q9D1N4
swissprot - E9QA72
Ensembl - ENSMUSG00000009214
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mymkENSDARG00000103988Danio rerio
 TMEM8CENSGALG00000021520Gallus gallus
 MYMKENSG00000187616Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tmem8 / Q9ESN3 / Post-GPI attachment to proteins factor 6 / Q9HCN3* / TMEM8A* / transmembrane protein 8A*ENSMUSG0000002418033
B1AWJ5 / Tmem8b / Mus musculus transmembrane protein 8B (Tmem8b), transcript variant 2, mRNA. / A6NDV4* / transmembrane protein 8B*ENSMUSG0000007871632


Protein motifs (from Interpro)
Interpro ID Name
 IPR021910  NGX6/PGAP6/MYMK


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0007520 myoblast fusion IEA
 biological_processGO:0014905 myoblast fusion involved in skeletal muscle regeneration IMP
 biological_processGO:0043403 skeletal muscle tissue regeneration IMP
 biological_processGO:0045026 plasma membrane fusion IDA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat/Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat
Genetic Background: involves: 129 * C57BL/6

 MP:0000733 abnormal muscle development "anomalous differentiation of muscle tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat/Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat
Genetic Background: involves: 129 * C57BL/6

 MP:0000753 paralysis "loss of power of voluntary movement in a muscle through injury or disease of its nerve supply" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat/Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat
Genetic Background: involves: 129 * C57BL/6

 MP:0006042 increased apoptosis "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat/Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat
Genetic Background: involves: 129 * C57BL/6

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat/Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat
Genetic Background: involves: 129 * C57BL/6

 MP:0011808 abnormal myoblast differentiation "anomaly in the process in which a relatively unspecialized cell acquires specialized features of a myoblast, a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers" [GO:0045445]
Show

Allelic Composition: Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat/Gt(ROSA)26Sortm5(CAG-Sun1/sfGFP)Nat
Genetic Background: involves: 129 * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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