ENSMUSG00000010154


Mus musculus

Features
Gene ID: ENSMUSG00000010154
  
Biological name :Spire2
  
Synonyms : 2 / Q8K1S6 / Spire2
  
Possible biological names infered from orthology : Q8WWL2 / spire type actin nucleation factor 2
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: E1
Gene start: 123332713
Gene end: 123369515
  
Corresponding Affymetrix probe sets: 10576288 (MoGene1.0st)   1425118_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000010298
Ensembl peptide - ENSMUSP00000148710
NCBI entrez gene - 234857     See in Manteia.
MGI - MGI:2446256
RefSeq - NM_172287
RefSeq Peptide - NP_758491
swissprot - Q8K1S6
Ensembl - ENSMUSG00000010154
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spire2ENSDARG00000003084Danio rerio
 SPIRE2ENSGALG00000000521Gallus gallus
 Q8WWL2ENSG00000204991Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
1 / Q52KF3 / Spire1 / Q08AE8* / spire type actin nucleation factor 1*ENSMUSG0000002453332


Protein motifs (from Interpro)
Interpro ID Name
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011019  KIND domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR029901  Protein Spire
 IPR029904  Protein Spire2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IMP
 biological_processGO:0030036 actin cytoskeleton organization IMP
 biological_processGO:0036089 cleavage furrow formation IMP
 biological_processGO:0040038 polar body extrusion after meiotic divisions IMP
 biological_processGO:0045010 actin nucleation IEA
 biological_processGO:0046907 intracellular transport IMP
 biological_processGO:0051295 establishment of meiotic spindle localization IMP
 biological_processGO:0070649 formin-nucleated actin cable assembly IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005938 cell cortex IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0032154 cleavage furrow IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003779 actin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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