MP:0000180 | abnormal circulating cholesterol level | "anomalous concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001402 | hypoactivity | "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001552 | increased circulating triglyceride level | "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002628 | fatty liver | "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Lepob/Lepob,Steap4tm1Dgen/Steap4tm1Dgen Genetic Background: involves: 129P2/OlaHsd
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MP:0002727 | decreased circulating insulin level | "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002970 | abnormal white fat morphology | "structural aberration in the connective tissue consisting of fat-storing cells and arranged in lobular groups or along minor blood vessels" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002981 | increased liver weight | "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0003383 | abnormal gluconeogenesis | "anomaly in the formation of glucose from noncarbohydrates, such as proteins or fat" [J:93896] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0003674 | oxidative stress | "condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0005266 | abnormal metabolism | "anomalous chemical and physical changes occurring in tissue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0005293 | impaired glucose tolerance | "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0005331 | insulin resistance | "diminished effectiveness of insulin in lowering plasma glucose levels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:84260, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0005425 | increased macrophage count | "greater than the normal numbers of macrophages" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:73418] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0005458 | increased percent body fat | "more fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Lepob/Lepob,Steap4tm1Dgen/Steap4tm1Dgen Genetic Background: involves: 129P2/OlaHsd
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MP:0005559 | increased circulating glucose level | "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Lepob/Lepob,Steap4tm1Dgen/Steap4tm1Dgen Genetic Background: involves: 129P2/OlaHsd
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MP:0005669 | increased circulating leptin level | "greater than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009355 | increased liver triglyceride level | "higher than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0010934 | increased subcutaneous adipose tissue amount | "increase in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0030017 | decreased adipocyte glucose uptake | "reduced ability of adipocytes to take in glucose" [MGI:anna] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0030022 | decreased muscle cell glucose uptake | "reduced ability of muscle cells to take in glucose" [MGI:anna] |
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Allelic Composition: Btbd9Gt(RRE078)Byg/Btbd9+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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