ENSMUSG00000013418


Mus musculus

Features
Gene ID: ENSMUSG00000013418
  
Biological name :B4galnt2
  
Synonyms : B4galnt2 / Beta-1,4 N-acetylgalactosaminyltransferase 2 / Q09199
  
Possible biological names infered from orthology : beta-1,4-N-acetyl-galactosaminyltransferase 2 / Q8NHY0
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 95865943
Gene end: 95914891
  
Corresponding Affymetrix probe sets: 10390196 (MoGene1.0st)   1421522_at (Mouse Genome 430 2.0 Array)   1439853_at (Mouse Genome 430 2.0 Array)   1441929_at (Mouse Genome 430 2.0 Array)   1442028_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000037239
NCBI entrez gene - 14422     See in Manteia.
MGI - MGI:1342058
RefSeq - XM_006532201
RefSeq - NM_008081
RefSeq Peptide - NP_032107
swissprot - Q09199
swissprot - A2A615
Ensembl - ENSMUSG00000013418
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 b4galnt2.1ENSDARG00000094579Danio rerio
 b4galnt2.2ENSDARG00000070605Danio rerio
 CABZ01039859.1ENSDARG00000076361Danio rerio
 Q8NHY0ENSG00000167080Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q09200 / B4galnt1 / Beta-1,4 N-acetylgalactosaminyltransferase 1 / Q00973* / beta-1,4-N-acetyl-galactosaminyltransferase 1*ENSMUSG0000000673139


Protein motifs (from Interpro)
Interpro ID Name
 IPR001173  Glycosyltransferase 2-like
 IPR011143  Ganglioside GM2 synthase
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006047 UDP-N-acetylglucosamine metabolic process IMP
 biological_processGO:0006486 protein glycosylation IMP
 biological_processGO:0019276 UDP-N-acetylgalactosamine metabolic process ISS
 biological_processGO:0022408 negative regulation of cell-cell adhesion ISS
 biological_processGO:0030259 lipid glycosylation IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030173 integral component of Golgi membrane IEA
 molecular_functionGO:0008376 acetylgalactosaminyltransferase activity ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0016758 transferase activity, transferring hexosyl groups IEA


Pathways (from Reactome)
Pathway description
Asparagine N-linked glycosylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000219 increased neutrophil count "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Spi1tm1.3Dgt/Spi1tm1.3Dgt
Genetic Background: involves: 129 * BALB/c * C57BL/6

 MP:0001488 increased startle reflex "reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Spi1tm1.3Dgt/Spi1tm1.3Dgt
Genetic Background: involves: 129 * BALB/c * C57BL/6

 MP:0002458 abnormal B cell number "deviation from the normal number of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Spi1tm1.3Dgt/Spi1tm1.3Dgt
Genetic Background: involves: 129 * BALB/c * C57BL/6

 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Spi1tm1.3Dgt/Spi1tm1.3Dgt
Genetic Background: involves: 129 * BALB/c * C57BL/6

 MP:0006143 increased diastolic blood pressure "abnormal increase in the pressure in the arteries between heart beats when the heart is relaxed" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Spi1tm1.3Dgt/Spi1tm1.3Dgt
Genetic Background: involves: 129 * BALB/c * C57BL/6

 MP:0008884 abnormal enterocyte apoptosis "change in the timing or the number of enterocytes undergoing programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: ApcMin/Apc+,Msh2tm1Htr/Msh2tm1Htr
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000030963 Umod / Q91X17 / uromodulin / P07911*  / reaction






 

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