ENSMUSG00000014329


Mus musculus

Features
Gene ID: ENSMUSG00000014329
  
Biological name :Bicc1
  
Synonyms : Bicc1 / Protein bicaudal C homolog 1 / Q99MQ1
  
Possible biological names infered from orthology : BicC family RNA binding protein 1 / Q9H694
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: B5.3
Gene start: 70922832
Gene end: 71159700
  
Corresponding Affymetrix probe sets: 10369842 (MoGene1.0st)   10369844 (MoGene1.0st)   1423484_at (Mouse Genome 430 2.0 Array)   1436029_at (Mouse Genome 430 2.0 Array)   1441137_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000014473
Ensembl peptide - ENSMUSP00000119137
Ensembl peptide - ENSMUSP00000123201
NCBI entrez gene - 83675     See in Manteia.
MGI - MGI:1933388
RefSeq - NM_031397
RefSeq - XM_006514341
RefSeq Peptide - NP_001334118
RefSeq Peptide - NP_113574
swissprot - G3X8S6
swissprot - Q99MQ1
Ensembl - ENSMUSG00000014329
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bicc1aENSDARG00000061682Danio rerio
 bicc1bENSDARG00000070497Danio rerio
 BICC1ENSGALG00000036095Gallus gallus
 BICC1ENSG00000122870Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Anks3 / Q9CZK6 / Ankyrin repeat and SAM domain-containing protein 3 / Q6ZW76* / ankyrin repeat and sterile alpha motif domain containing 3*ENSMUSG0000002251510


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR004087  K Homology domain
 IPR004088  K Homology domain, type 1
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR036612  K Homology domain, type 1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway ISO
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000284 double outlet right ventricle "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826]
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Allelic Composition: Dnaic1b2b284Clo/Dnaic1b2b284Clo
Genetic Background: C57BL/6J-Dnaic1b2b284Clo

 MP:0000522 cysts in kidney cortex "abnormal membranous sacs appearing in the renal lobules, tubules and glomeruli" [J:50844]
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Allelic Composition: Tnftm2Jods/Tnftm2Jods
Genetic Background: C57BL/6-Tnftm2Jods

 MP:0000598 abnormal liver morphology "malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:23170]
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Allelic Composition: Csrp3tm1Crni/Csrp3tm1Crni,Plntm1Egk/Plntm1Egk
Genetic Background: involves: 129S2/SvPas * CF1

Allelic Composition: Bicc1jcpk-67Gso/Bicc1jcpk-67Gso,T(2;10)67Gso/T(2;10)67Gso
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso

 MP:0000603 pale liver "liver lacking normal coloration, often refers to bloodless condition" [J:18048]
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Allelic Composition: Bicc1jcpk-bpk/Bicc1jcpk-bpk
Genetic Background: involves: BALB/c * CAST/EiJ

Allelic Composition: Bicc1jcpk/Bicc1jcpk-bpk
Genetic Background: involves: 101 * BALB/c * C3H * C57BL/6J * T STOCK

 MP:0000611 jaundice "clinical manifestation of hyperbilirubinemia, with deposition of bile pigments in the skin, resulting in yellowish staining of the skin and mucous membranes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Bicc1jcpk-67Gso/Bicc1jcpk-67Gso,T(2;10)67Gso/T(2;10)67Gso
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso

 MP:0000644 dextrocardia "cardiac apex pointing to the right as opposed to the normal levocardia" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Dnaic1b2b284Clo/Dnaic1b2b284Clo
Genetic Background: C57BL/6J-Dnaic1b2b284Clo

 MP:0000746 weakness "state of being infirm or less strong than littermates" [J:45400]
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Allelic Composition: Bicc1jcpk-67Gso/Bicc1jcpk-67Gso,T(2;10)67Gso/T(2;10)67Gso
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Bicc1jcpk-bpk/Bicc1jcpk-bpk
Genetic Background: involves: BALB/c * CAST/EiJ

Allelic Composition: Bicc1jcpk/Bicc1jcpk
Genetic Background: involves: 101 * C3H * T STOCK

 MP:0001270 distended abdomen "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Csrp3tm1Crni/Csrp3tm1Crni,Plntm1Egk/Plntm1Egk
Genetic Background: involves: 129S2/SvPas * CF1

Allelic Composition: Bicc1jcpk-bpk/Bicc1jcpk-bpk
Genetic Background: involves: BALB/c * CAST/EiJ

Allelic Composition: Bicc1jcpk/Bicc1jcpk-bpk
Genetic Background: involves: 101 * BALB/c * C3H * C57BL/6J * T STOCK

Allelic Composition: Bicc1jcpk/Bicc1jcpk
Genetic Background: involves: 101 * C3H * T STOCK

Allelic Composition: Bicc1jcpk/T(2;10)67Gso
Genetic Background: involves: 101 * C3H * C3H/Rl * C57BL/6 * C57BL/RlGso * SEC/RlGso

Allelic Composition: Bicc1jcpk-67Gso/Bicc1jcpk-67Gso,T(2;10)67Gso/T(2;10)67Gso
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso

 MP:0001924 infertility "inability to produce live offspring" [J:47225]
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Allelic Composition: Bicc1m1Btlr/Bicc1m1Btlr
Genetic Background: C57BL/6J-Bicc1m1Btlr

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Csrp3tm1Crni/Csrp3tm1Crni,Plntm1Egk/Plntm1Egk
Genetic Background: involves: 129S2/SvPas * CF1

Allelic Composition: Bicc1m1Btlr/Bicc1m1Btlr
Genetic Background: C57BL/6J-Bicc1m1Btlr

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tpi1a-m6Neu/Tpi1+
Genetic Background: involves: 101/El * C3H/El

 MP:0002766 situs inversus "lateral transposition of the viscera of the thorax and abdomen, sometimes incomplete" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Szt2Gt(XH662)Byg/Szt2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0002767 situs ambiguus "abnormal organ position" [J:62608]
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Allelic Composition: Szt2Gt(XH662)Byg/Szt2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0002928 abnormal bile duct morphology "malformation of the channels that secrete bile from the liver to the gall bladder and intestines" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Tnftm2Jods/Tnftm2Jods
Genetic Background: C57BL/6-Tnftm2Jods

Allelic Composition: Bicc1jcpk/Bicc1jcpk-bpk
Genetic Background: involves: 101 * BALB/c * C3H * C57BL/6J * T STOCK

 MP:0003068 enlarged kidney "larger than average size of the kidney" [J:86005, pvb:Pierre Vanden Borre, Mouse Genome Informatics Curator]
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Allelic Composition: Csrp3tm1Crni/Csrp3tm1Crni,Plntm1Egk/Plntm1Egk
Genetic Background: involves: 129S2/SvPas * CF1

Allelic Composition: Bicc1jcpk-bpk/Bicc1jcpk-bpk
Genetic Background: involves: BALB/c * CAST/EiJ

Allelic Composition: Bicc1jcpk/Bicc1jcpk-bpk
Genetic Background: involves: 101 * BALB/c * C3H * C57BL/6J * T STOCK

Allelic Composition: Bicc1jcpk/T(2;10)67Gso
Genetic Background: involves: 101 * C3H * C3H/Rl * C57BL/6 * C57BL/RlGso * SEC/RlGso

Allelic Composition: Bicc1tm1Emdr/Bicc1tm1Emdr
Genetic Background: B6SJL-Bicc1tm1Emdr/J

Allelic Composition: Bicc1jcpk-67Gso/Bicc1jcpk-67Gso,T(2;10)67Gso/T(2;10)67Gso
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso

 MP:0003253 bile duct dilation "abnormal distention of the bile ducts due to accumulation of fluid or bile" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Bicc1jcpk/Bicc1jcpk
Genetic Background: involves: 101 * C3H * T STOCK

 MP:0003266 biliary cysts "the appearance of fluid-filled sacs within the bile ducts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Bicc1tm1Emdr/Bicc1tm1Emdr
Genetic Background: B6SJL-Bicc1tm1Emdr/J

Allelic Composition: Bicc1jcpk-67Gso/Bicc1jcpk-67Gso,T(2;10)67Gso/T(2;10)67Gso
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso

 MP:0003336 pancreatic cysts "the appearance of fluid-filled sacs within the pancreas" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Bicc1tm1Emdr/Bicc1tm1Emdr
Genetic Background: B6SJL-Bicc1tm1Emdr/J

 MP:0003606 kidney failure "cessation of renal function" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Csrp3tm1Crni/Csrp3tm1Crni,Plntm1Egk/Plntm1Egk
Genetic Background: involves: 129S2/SvPas * CF1

Allelic Composition: Bicc1tm1Bdc/Bicc1tm1Bdc
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0003675 kidney cysts "abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Csrp3tm1Crni/Csrp3tm1Crni,Plntm1Egk/Plntm1Egk
Genetic Background: involves: 129S2/SvPas * CF1

Allelic Composition: Bicc1jcpk-bpk/Bicc1jcpk-bpk
Genetic Background: involves: BALB/c * CAST/EiJ

Allelic Composition: Bicc1jcpk/Bicc1jcpk-bpk
Genetic Background: involves: 101 * BALB/c * C3H * C57BL/6J * T STOCK

Allelic Composition: Bicc1jcpk/Bicc1jcpk
Genetic Background: involves: 101 * C3H * T STOCK

Allelic Composition: Bicc1jcpk/Bicc1+
Genetic Background: involves: 101 * C3H * T STOCK

Allelic Composition: Bicc1jcpk-67Gso/Bicc1jcpk-67Gso,T(2;10)67Gso/T(2;10)67Gso
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso

Allelic Composition: Bicc1m1006Lja/Bicc1m1006Lja
Genetic Background: C57BL/6J-Bicc1m1006Lja

 MP:0004133 heterotaxia "abnormal arrangement of organs or parts of the body in relation to each other" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Dnaic1b2b284Clo/Dnaic1b2b284Clo
Genetic Background: C57BL/6J-Dnaic1b2b284Clo

 MP:0004839 bile duct hyperplasia "overdevelopment or increased size of the bile ducts, usually due to an increase in the number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Csrp3tm1Crni/Csrp3tm1Crni,Plntm1Egk/Plntm1Egk
Genetic Background: involves: 129S2/SvPas * CF1

 MP:0005202 lethargy "mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Csrp3tm1Crni/Csrp3tm1Crni,Plntm1Egk/Plntm1Egk
Genetic Background: involves: 129S2/SvPas * CF1

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Csrp3tm1Crni/Csrp3tm1Crni,Plntm1Egk/Plntm1Egk
Genetic Background: involves: 129S2/SvPas * CF1

Allelic Composition: Bicc1m1Btlr/Bicc1m1Btlr
Genetic Background: C57BL/6J-Bicc1m1Btlr

 MP:0008528 polycystic kidney "the development of innumerable cysts in the kidneys filled with fluid replacing much of the mass of the kidneys leading to reduction in kidney function and frequently kidney failure" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Bicc1jcpk/T(2;10)67Gso
Genetic Background: involves: 101 * C3H * C3H/Rl * C57BL/6 * C57BL/RlGso * SEC/RlGso

Allelic Composition: Bicc1tm1Emdr/Bicc1tm1Emdr
Genetic Background: B6SJL-Bicc1tm1Emdr

Allelic Composition: Bicc1m1Btlr/Bicc1m1Btlr
Genetic Background: C57BL/6J-Bicc1m1Btlr

Allelic Composition: Bicc1tm1Emdr/Bicc1tm1Emdr
Genetic Background: B6SJL-Bicc1tm1Emdr/J

Allelic Composition: Bicc1b2b222Clo/Bicc1b2b222Clo
Genetic Background: C57BL/6J-Bicc1b2b222Clo

 MP:0008933 abnormal embryonic cilium physiology "any functional anomaly of the earliest cilia of the mouse embryo found on the cells of the embryonic node" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Bicc1tm1Bdc/Bicc1tm1Bdc
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0008986 abnormal liver parenchyma morphology "any structural anomaly of the functional units of the liver including the lobules" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bicc1jcpk-67Gso/Bicc1jcpk-67Gso,T(2;10)67Gso/T(2;10)67Gso
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso

 MP:0008992 abnormal portal lobule morphology "any structural anomaly of the triangular region on the periphery of the liver lobules that contain a bile duct and a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Bicc1jcpk/Bicc1jcpk-bpk
Genetic Background: involves: 101 * BALB/c * C3H * C57BL/6J * T STOCK

 MP:0008993 abnormal portal triad morphology "any structural anomaly of the three vessels of the portal lobule including the bile duct, a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Tnftm2Jods/Tnftm2Jods
Genetic Background: C57BL/6-Tnftm2Jods

Allelic Composition: Bicc1jcpk/Bicc1jcpk-bpk
Genetic Background: involves: 101 * BALB/c * C3H * C57BL/6J * T STOCK

 MP:0009144 dilated pancreatic duct "an increase in volume of the luminal space of the excretory duct of the exocrine pancreas that collects fluid containing digestive enzymes and transports it to the duodenum" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A03.734.667]
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Allelic Composition: Bicc1jcpk/Bicc1jcpk
Genetic Background: involves: 101 * C3H * T STOCK

 MP:0009342 enlarged gall bladder "increased size of the gall bladder, the organ that serves as a storage reservoir for bile" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Bicc1jcpk/Bicc1jcpk
Genetic Background: involves: 101 * C3H * T STOCK

 MP:0009343 dilated gall bladder "abnormal distention of the gall bladder due to accumulation of fluid or bile" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Bicc1jcpk-bpk/Bicc1jcpk-bpk
Genetic Background: involves: BALB/c * CAST/EiJ

Allelic Composition: Bicc1jcpk/Bicc1jcpk-bpk
Genetic Background: involves: 101 * BALB/c * C3H * C57BL/6J * T STOCK

 MP:0009494 abnormal biliary ductule morphology "any structural anomaly of the excretory ducts of the liver that connect the interlobular ductules to the right or left hepatic duct" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Bicc1jcpk-67Gso/Bicc1jcpk-67Gso,T(2;10)67Gso/T(2;10)67Gso
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso

 MP:0009500 abnormal interlobular bile duct morphology "any structural anomaly of the canals that carry bile in the liver between the intralobular ducts and the biliary ductules; interlobular bile ducts are part of the interlobular portal triad" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Bicc1jcpk-67Gso/Bicc1jcpk-67Gso,T(2;10)67Gso/T(2;10)67Gso
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso

 MP:0009703 decreased birth body size "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Bicc1jcpk-67Gso/Bicc1jcpk-67Gso,T(2;10)67Gso/T(2;10)67Gso
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso

 MP:0010402 ventricular septal defect "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]
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Allelic Composition: Bicc1tm1Bdc/Bicc1tm1Bdc
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0010412 atrioventricular septal defect "defects in the thin membranous structure between the right atrium and left ventricle that arise from faulty development of the embryonic endocardial cushions; the spectrum ranges from a primum atrial septal defect and cleft mitral valve, known as a partial atrioventricular septal defect (partial AVSD), to defects of both the primum atrial septum and inlet ventricular septum and the presence of a common atrioventricular valve, referred to as complete atrioventricular septal defect (complete AVSD)" [http://emedicine.medscape.com]
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Allelic Composition: Bicc1b2b222Clo/Bicc1b2b222Clo
Genetic Background: C57BL/6J-Bicc1b2b222Clo

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Csrp3tm1Crni/Csrp3tm1Crni,Plntm1Egk/Plntm1Egk
Genetic Background: involves: 129S2/SvPas * CF1

Allelic Composition: Bicc1jcpk-bpk/Bicc1jcpk-bpk
Genetic Background: involves: BALB/c * CAST/EiJ

Allelic Composition: Bicc1jcpk/Bicc1jcpk
Genetic Background: involves: 101 * C3H * T STOCK

Allelic Composition: Bicc1tm1Emdr/Bicc1tm1Emdr
Genetic Background: B6SJL-Bicc1tm1Emdr

Allelic Composition: Bicc1tm1Bdc/Bicc1tm1Bdc
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Bicc1jcpk-67Gso/Bicc1jcpk-67Gso,T(2;10)67Gso/T(2;10)67Gso
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Bicc1jcpk-67Gso/Bicc1jcpk-67Gso,T(2;10)67Gso/T(2;10)67Gso
Genetic Background: involves: 101/Rl * C3H/Rl * C57BL10a/E * SEC/RlGso

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Bicc1tm1Emdr/Bicc1tm1Emdr
Genetic Background: B6SJL-Bicc1tm1Emdr/J

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Bicc1tm1Bdc/Bicc1tm1Bdc
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0011109 partial lethality throughout fetal growth and development "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
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Allelic Composition: Bicc1tm1Emdr/Bicc1tm1Emdr
Genetic Background: B6SJL-Bicc1tm1Emdr/J

 MP:0011252 situs inversus totalis "the complete right to left reversal (transposition) of the thoracic and abdominal organs, including the heart (dextrocardia)" [MGI:csmith]
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Allelic Composition: Bicc1b2b222Clo/Bicc1b2b222Clo
Genetic Background: C57BL/6J-Bicc1b2b222Clo

 MP:0011334 abnormal nephrogenic zone morphology "any structural anomaly in the region found at the periphery of the developing metanephros within which the metanephric mesenchyme aggregates around the tips of the ureteric tree to form the nephrons; in rodents including mice, this region normally disappears within the first postnatal week when nephrogenesis ceases and only mature nephrons are present; in humans, it is lost by 36 weeks of gestation" [PMID:17452023]
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Allelic Composition: Bicc1tm1Emdr/Bicc1tm1Emdr
Genetic Background: B6SJL-Bicc1tm1Emdr/J

 MP:0011501 increased glomerular capsule space "increased volume of the luminal region between the glomerular capsule visceral and parietal layers, into which filtrate enters after passing through the filtration barrier from the glomerular capillaries" [MGI:csmith]
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Allelic Composition: Csrp3tm1Crni/Csrp3tm1Crni,Plntm1Egk/Plntm1Egk
Genetic Background: involves: 129S2/SvPas * CF1

Allelic Composition: Bicc1jcpk/Bicc1jcpk
Genetic Background: involves: 101 * C3H * C57BL/6J * T STOCK

 MP:0011665 d-loop transposition of the great arteries "complete transposition of the great arteries; the d- refers to the dextroposition of the bulboventricular loop (ie, the position of the right ventricle, which is on the right side); in addition, the aorta also tends to be on the right and anterior, and the great arteries are parallel rather than crossing" [PMID:17159076]
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Allelic Composition: Bicc1b2b222Clo/Bicc1b2b222Clo
Genetic Background: C57BL/6J-Bicc1b2b222Clo

 MP:0012027 abnormal embryonic cilium location or orientation "embryonic cilia are displaced from the normal position and/or do not orient in a typical pattern" [MGI:csmith]
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Allelic Composition: Bicc1tm1Bdc/Bicc1tm1Bdc
Genetic Background: involves: 129/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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