ENSMUSG00000015377


Mus musculus

Features
Gene ID: ENSMUSG00000015377
  
Biological name :Dennd6b
  
Synonyms : Dennd6b / Protein DENND6B / Q9D9V7
  
Possible biological names infered from orthology : DENN domain containing 6B / Q8NEG7
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E3
Gene start: 89182213
Gene end: 89196496
  
Corresponding Affymetrix probe sets: 10431463 (MoGene1.0st)   1436140_at (Mouse Genome 430 2.0 Array)   1438638_x_at (Mouse Genome 430 2.0 Array)   1447603_x_at (Mouse Genome 430 2.0 Array)   1452706_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000077978
Ensembl peptide - ENSMUSP00000155612
NCBI entrez gene - 69440     See in Manteia.
MGI - MGI:1916690
RefSeq - NM_027081
RefSeq Peptide - NP_081357
swissprot - Q9D9V7
Ensembl - ENSMUSG00000015377
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dennd6bENSDARG00000011605Danio rerio
 DENND6BENSGALG00000043771Gallus gallus
 Q8NEG7ENSG00000205593Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BH65 / Dennd6a / Protein DENND6A / Q8IWF6* / DENN domain containing 6A*ENSMUSG0000004081858


Protein motifs (from Interpro)
Interpro ID Name
 IPR018307  AVL9/DENND6 domain
 IPR024224  DENND6
 IPR037516  Tripartite DENN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0055037 recycling endosome IBA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity IBA


Pathways (from Reactome)
Pathway description
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000015291 Gdi1 / P50396 / Rab GDP dissociation inhibitor alpha / P31150* / GDP dissociation inhibitor 1*  / reaction
 ENSMUSG00000026878 Rab14 / Q91V41 / RAB14, member RAS oncogene family / P61106*  / reaction
 ENSMUSG00000025531 Chm / choroidermia (RAB escort protein 1) / P24386* / CHM, Rab escort protein 1*  / reaction
 ENSMUSG00000021218 Gdi2 / Q61598 / Rab GDP dissociation inhibitor beta / P50395* / GDP dissociation inhibitor 2*  / reaction
 ENSMUSG00000078185 Chml / choroideremia-like / P26374* / CHM like, Rab escort protein 2*  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr