ENSMUSG00000015852


Mus musculus

Features
Gene ID: ENSMUSG00000015852
  
Biological name :Fcrls
  
Synonyms : Fcrls
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F1
Gene start: 87250758
Gene end: 87263738
  
Corresponding Affymetrix probe sets: 10499189 (MoGene1.0st)   1448891_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115780
Ensembl peptide - ENSMUSP00000088508
NCBI entrez gene - 80891     See in Manteia.
MGI - MGI:1933397
RefSeq - NM_030707
RefSeq - XM_006502369
RefSeq Peptide - NP_109632
swissprot - D3YYJ5
swissprot - Q9EQY5
Ensembl - ENSMUSG00000015852
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FCRL4ENSGALG00000010507Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fcrl5 / Q68SN8 / Fc receptor-like protein 5 / Q96RD9* / Fc receptor like 5*ENSMUSG0000004803130
Fcrl1 / Q96LA6* / Fc receptor like 1*ENSMUSG0000005999422
Fcgr1 / P26151 / High affinity immunoglobulin gamma Fc receptor I / Q92637* / FCGR1A* / FCGR1B* / P12314* / Fc fragment of IgG receptor Ib* / Fc fragment of IgG receptor Ia*ENSMUSG0000001594714
Fcrla / Q920A9 / Fc receptor-like A / Q7L513*ENSMUSG0000003842114
Fcrlb / Q5DRQ8 / Fc receptor-like B / Q6BAA4*ENSMUSG0000007052414
Fcrl6 / A1YIY0 / Fc receptor-like protein 6 ENSMUSG0000007050412
Fcgr2b / P31994* / FCGR2A* / FCGR2C* / P12318* / Fc fragment of IgG receptor IIa* / Fc fragment of IgG receptor IIb* / Fc fragment of IgG receptor IIc (gene/pseudogene)*ENSMUSG000000266568
Fcgr4 / A0A0B4J1G0 / Low affinity immunoglobulin gamma Fc region receptor IV / P08637* / FCGR3A* / FCGR3B* / O75015* / Fc fragment of IgG receptor IIIa* / Fc fragment of IgG receptor IIIb*ENSMUSG000000590897
Fcer1a / P20489 / High affinity immunoglobulin epsilon receptor subunit alpha / P12319* / Fc fragment of IgE receptor Ia*ENSMUSG000000053396
Fcgr3 / Mus musculus Fc receptor, IgG, low affinity III (Fcgr3), transcript variant 2, mRNA. / FCGR2C* / P31994* / FCGR2A* / FCGR2B* / P12318* / Fc fragment of IgG receptor IIb* / Fc fragme...ENSMUSG000000594986


Protein motifs (from Interpro)
Interpro ID Name
 IPR001190  SRCR domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR017448  SRCR-like domain
 IPR036179  Immunoglobulin-like domain superfamily
 IPR036772  SRCR-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005044 scavenger receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Tmprss6hem8/Tmprss6tm1Dgen
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0001264 increased body size "larger than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401]
Show

Allelic Composition: Tmprss6hem8/Tmprss6tm1Dgen
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Tmprss6hem8/Tmprss6tm1Dgen
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0008079 decreased CD8-positive T cell number "reduction in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tmprss6hem8/Tmprss6tm1Dgen
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0010024 increased total body fat amount "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tmprss6hem8/Tmprss6tm1Dgen
Genetic Background: involves: C57BL/6 * C57BL/6J

 MP:0012323 increased total tissue mass "increased physical bulk or volume of the body including lean body mass, fat body mass, and bone tissue" [MPD:Molly]
Show

Allelic Composition: Tmprss6hem8/Tmprss6tm1Dgen
Genetic Background: involves: C57BL/6 * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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