MP:0000188 | abnormal circulating glucose level | "anomalous concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Pou4f2tm1Rsd/Pou4f2tm1Rsd Genetic Background: involves: 129S4/SvJae
|
MP:0000495 | abnormal colon morphology | "malformation of the portion of the large intestine between the cecum and the rectum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Chrnetm1Vwi/Chrnetm1Vwi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Gasttm1Tcw/Gasttm1Tcw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
MP:0000501 | abnormal digestive secretion | "malfunction of the production and/or release of a physiologically active substance (usually but not exclusively in liquid form) from a cell or a gland of the digestive system" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc] |
Show
Allelic Composition: Gasttm1Tcw/Gasttm1Tcw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Gasttm1Lcs/Gast+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
MP:0001663 | abnormal digestive system physiology | "altered function of the organ system that converts ingested food to nutrients and energy" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Gasttm1Tcw/Gasttm1Tcw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
MP:0001873 | stomach inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the stomach" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
Show
Allelic Composition: Gasttm1Tcw/Gasttm1Tcw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
MP:0002079 | increased circulating insulin level | "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Pou4f2tm1Rsd/Pou4f2tm1Rsd Genetic Background: involves: 129S4/SvJae
|
MP:0003564 | abnormal insulin secretion | "aberrant release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Pou4f2tm1Rsd/Pou4f2tm1Rsd Genetic Background: involves: 129S4/SvJae
|
MP:0003892 | abnormal gastric gland | "anomaly of any of the branched tubular glands in the mucosa of the fundus and body of the stomach that contain parietal cells that secrete hydrocholric acid and zymogenic cells that produce pepsin " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Gasttm1Tcw/Gasttm1Tcw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Atp4btm1Ird/Atp4btm1Ird,Gasttm1Lcs/Gasttm1Lcs Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/cCrSlc
|
MP:0004138 | abnormal mucous neck cell morphology | "malformation of the mucin-producing epithelial cells present in the the neck of the gastric glands " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Gasttm1Tcw/Gasttm1Tcw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
MP:0004139 | abnormal parietal cell morphology | "malformation of the gastric acid producing epithelial cells that are distributed throughout the length of the gastric gland " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Gasttm1Tcw/Gasttm1Tcw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Gasttm1Lcs/Gasttm1Lcs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Atp4btm1Ird/Atp4btm1Ird,Gasttm1Lcs/Gasttm1Lcs Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/cCrSlc
|
MP:0004140 | abnormal chief cell morphology | "malformation of the pepsinogen producing epithelial cells that are clustered at the base of the gastric gland " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Gasttm1Tcw/Gasttm1Tcw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Atp4btm1Ird/Atp4btm1Ird,Gasttm1Lcs/Gasttm1Lcs Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/cCrSlc
|
MP:0004151 | hypoferremia | "less than the normal concentration of this metallic element in the blood" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Cckbrtm1Tom/Cckbr+ Genetic Background: B6.129S4-Cckbrtm1Tom
|
MP:0004499 | increased incidence of chemically-induced tumors | "higher than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Chrnetm1Vwi/Chrnetm1Vwi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
MP:0005292 | improved glucose tolerance | "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Pou4f2tm1Rsd/Pou4f2tm1Rsd Genetic Background: involves: 129S4/SvJae
|
MP:0005637 | abnormal iron homeostasis | "anomaly in the state of equilibrium in the body with respect to this metallic element that normally occurs in the heme of hemoglobin, myoglobin, transferrin, ferritin, and iron-containing porphyrins; it is an essential component of enzymes such as catalase, peroxidase, and various cytochromes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:64456] |
Show
Allelic Composition: Cckbrtm1Tom/Cckbr+ Genetic Background: B6.129S4-Cckbrtm1Tom
|
MP:0008006 | increased stomach pH | "change in the function of the secretory and buffer systems of the stomach that control the relative acidity or alkalinity, such that the acidity is decreased, as indicated by the decreased concentration of hydrogen ion" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Gasttm1Tcw/Gasttm1Tcw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
MP:0008873 | increased sensitivity to xenobiotics | "decrease in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Chrnetm1Vwi/Chrnetm1Vwi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
|
MP:0010301 | increased stomach tumor incidence | "greater than the expected number of neoplasms in the gastric tissue usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Gasttm1Lcs/Gasttm1Lcs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
|
MP:0010792 | abnormal stomach mucosa morphology | "any structural anomaly of the mucous layer of the stomach wall which contains the gastric pits and glands, and consists of epithelium, lamina propria, and the muscularis mucosae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Gasttm1Tcw/Gasttm1Tcw Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Gasttm1Lcs/Gasttm1Lcs Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Atp4btm1Ird/Atp4btm1Ird,Gasttm1Lcs/Gasttm1Lcs Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/cCrSlc
|
MP:0011896 | increased circulating unsaturated transferrin level | "increase in the concentration of transferrin that is not saturated (bound) with iron; this represents the reserve capacity of transferrin and is often measured by the Unsaturated Iron Binding Capacity (UIBC) test" [MGI:csmith] |
Show
Allelic Composition: Cckbrtm1Tom/Cckbr+ Genetic Background: B6.129S4-Cckbrtm1Tom
|