Manteia

ENSMUSG00000017802

Mus musculus

Features

Gene ID:	ENSMUSG00000017802

Biological name :	Retreg3

Synonyms :	Q9CQV4 / Reticulophagy regulator 3 / Retreg3

Possible biological names infered from orthology :	Q86VR2 / reticulophagy regulator family member 3

Species:	Mus musculus

Chr. number:	11
Strand:	-1
Band:	D
Gene start:	101096322
Gene end:	101119893

Corresponding Affymetrix probe sets:	10391348 (MoGene1.0st) 1424159_at (Mouse Genome 430 2.0 Array) 1431926_a_at (Mouse Genome 430 2.0 Array) 1447884_x_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000017946 Ensembl peptide - ENSMUSP00000102916 NCBI entrez gene - 67998 See in Manteia. MGI - MGI:1915248 RefSeq - XM_006534032 RefSeq - NM_026501 RefSeq - NM_028933 RefSeq Peptide - NP_083209 RefSeq Peptide - NP_080777 swissprot - Q9CQV4 Ensembl - ENSMUSG00000017802

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
retreg3	ENSDARG00000059804	Danio rerio
RETREG3	ENSGALG00000003162	Gallus gallus
Q86VR2	ENSG00000141699	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Q8VE91 / Fam134b / Reticulophagy regulator 1 / Q9H6L5* / RETREG1*	ENSMUSG00000022270	32
Q6NS82 / Retreg2 / Reticulophagy regulator 2 / Q8NC44* / reticulophagy regulator family member 2*	ENSMUSG00000049339	32

Protein motifs (from Interpro)

Interpro ID	Name
IPR033361	Reticulophagy regulator 3

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0010976	positive regulation of neuron projection development	ISO
cellular_component	GO:0005575	cellular_component	ND
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0003674	molecular_function	ND

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Elmod1^{tm1a(EUCOMM)Hmgu}/Elmod1^{tm1a(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Elmod1^{tm1a(EUCOMM)Hmgu}/H
MP:0001325	abnormal retina morphology	"structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fadd^{tm1e.1(KOMP)Wtsi}/Fadd^{tm1e.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Fadd^{tm1e.1(KOMP)Wtsi}/Ucd
MP:0002764	short tibia	" reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Fadd^{tm1e.1(KOMP)Wtsi}/Fadd^{tm1e.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Fadd^{tm1e.1(KOMP)Wtsi}/Ucd
MP:0002874	decreased hemoglobin content	"decrease in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Elmod1^{tm1a(EUCOMM)Hmgu}/Elmod1^{tm1a(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Elmod1^{tm1a(EUCOMM)Hmgu}/H
MP:0002968	increased circulating alkaline phosphatase level	"elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Fadd^{tm1e.1(KOMP)Wtsi}/Fadd^{tm1e.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Fadd^{tm1e.1(KOMP)Wtsi}/Ucd
MP:0003795	abnormal bone structure		Show Allelic Composition: Fadd^{tm1e.1(KOMP)Wtsi}/Fadd^{tm1e.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Fadd^{tm1e.1(KOMP)Wtsi}/Ucd
MP:0003921	abnormal left ventricle morphology	"structural anomaly of the left lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Fadd^{tm1e.1(KOMP)Wtsi}/Fadd^{tm1e.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Fadd^{tm1e.1(KOMP)Wtsi}/Ucd
MP:0003960	increased lean body mass	"more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]	Show Allelic Composition: Fadd^{tm1e.1(KOMP)Wtsi}/Fadd^{tm1e.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Fadd^{tm1e.1(KOMP)Wtsi}/Ucd
MP:0005560	decreased circulating glucose level	"less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fadd^{tm1e.1(KOMP)Wtsi}/Fadd^{tm1e.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Fadd^{tm1e.1(KOMP)Wtsi}/Ucd
MP:0009142	decreased prepulse inhibition	"decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fadd^{tm1e.1(KOMP)Wtsi}/Fadd^{tm1e.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Fadd^{tm1e.1(KOMP)Wtsi}/Ucd
MP:0010025	decreased total body fat amount	"less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fadd^{tm1e.1(KOMP)Wtsi}/Fadd^{tm1e.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Fadd^{tm1e.1(KOMP)Wtsi}/Ucd
MP:0010124	decreased bone mineral content	"reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fadd^{tm1e.1(KOMP)Wtsi}/Fadd^{tm1e.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Fadd^{tm1e.1(KOMP)Wtsi}/Ucd

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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