ENSMUSG00000018819


Mus musculus

Features
Gene ID: ENSMUSG00000018819
  
Biological name :Lsp1
  
Synonyms : Lsp1 / Lymphocyte-specific protein 1 / P19973
  
Possible biological names infered from orthology : P33241
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F5
Gene start: 142460809
Gene end: 142494867
  
Corresponding Affymetrix probe sets: 10559207 (MoGene1.0st)   1417756_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000101587
Ensembl peptide - ENSMUSP00000101586
Ensembl peptide - ENSMUSP00000101588
Ensembl peptide - ENSMUSP00000147933
Ensembl peptide - ENSMUSP00000147500
Ensembl peptide - ENSMUSP00000018963
Ensembl peptide - ENSMUSP00000040637
NCBI entrez gene - 16985     See in Manteia.
MGI - MGI:96832
RefSeq - XM_006508496
RefSeq - NM_001136071
RefSeq - NM_001271508
RefSeq - NM_001271509
RefSeq - NM_001271510
RefSeq - NM_001271523
RefSeq - NM_019391
RefSeq - XM_006508494
RefSeq - XM_006508495
RefSeq Peptide - NP_001258438
RefSeq Peptide - NP_001258439
RefSeq Peptide - NP_001258452
RefSeq Peptide - NP_062264
RefSeq Peptide - NP_001258437
RefSeq Peptide - NP_001129543
swissprot - P19973
swissprot - A2A6J7
swissprot - A2A6J4
swissprot - A0A1B0GSH0
swissprot - A0A1B0GRF5
Ensembl - ENSMUSG00000018819
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LSP1ENSGALG00000006583Gallus gallus
 LSP1ENSG00000130592Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002211  Lymphocyte-specific protein
 IPR006018  Caldesmon/lymphocyte specific protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0006935 chemotaxis IMP
 biological_processGO:0006952 defense response IMP
 biological_processGO:0007010 cytoskeleton organization TAS
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003779 actin binding TAS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000685 abnormal immune system morphology "morphological anomalies in the organs or cells associated with the development and formation of lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Chrm3tm1Mmt/Chrm3tm1Mmt
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002401 abnormal lymphopoiesis "atypcial formation of lymphocytes and plasma cells from lymphoid stem cells which develop from the pluripotent hematopoietic stem cells in the bone marrow; these lymphoid stem cells differentiate into T-lymphocytes; B-lymphocytes; plasma cells; or NK-cells (natural killer cells), depending on the organ or tissues to which they migrate" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Chrm3tm1Mmt/Chrm3tm1Mmt
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002442 abnormal leukocyte physiology "abnormal function of any of the white blood cells (basophils, eosinophils, neutrophils, lymphocytes, or monocytes) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Chrm3tm1Mmt/Chrm3tm1Mmt
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0005425 increased macrophage count "greater than the normal numbers of macrophages" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:73418]
Show

Allelic Composition: Chrm3tm1Mmt/Chrm3tm1Mmt
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0008720 impaired neutrophil migration "defect in the ability of neutrophils to move along a chemotactic gradient" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Chrm3tm1Mmt/Chrm3tm1Mmt
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0009858 abnormal cellular extravasation "any anomaly in the migration of leukocytes from the blood vessels into the surrounding tissue" [GO:0045123]
Show

Allelic Composition: Chrm3tm1Mmt/Chrm3tm1Mmt
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr