MP:0000266 | abnormal cardiac morphology | "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Col1a1tm1.1Jcm/Col1a1+ Genetic Background: either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1)
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MP:0001574 | abnormal oxygen level | "anomalous concentration of this gaseous element, essential for animal and plant life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Col1a1tm1.1Jcm/Col1a1+ Genetic Background: either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1)
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MP:0001622 | abnormal vasculogenesis | "aberrant process of the initial establishment of the vascular network " [J:67296, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Pdx1tm1Ted/Pdx1+ Genetic Background: involves: 129P2/OlaHsd
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MP:0001625 | cardiac hypertrophy | "an increase in size of the cardiac tissue, not due to increased cell number " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Mbtm1Wlm/Mbtm1Wlm Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
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MP:0001698 | reduced embryo size | "smaller proportions of embryo compared to littermates" [J:61790] |
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Allelic Composition: Pdx1tm1Ted/Pdx1+ Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Mbtm1Wlm/Mb+ Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
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MP:0001785 | edema | "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065] |
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Allelic Composition: Pdx1tm1Ted/Pdx1+ Genetic Background: involves: 129P2/OlaHsd
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MP:0001914 | hemorrhage | "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Pdx1tm1Ted/Pdx1+ Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Mbtm1Wlm/Mb+ Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
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MP:0002608 | increased hematocrit | "greater than average percentage of a volume of a blood sample occupied by red blood cells" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Col1a1tm1.1Jcm/Col1a1+ Genetic Background: either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1)
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MP:0002625 | left ventricle hypertrophy | "increased size of the left ventricle" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Mbtm1Wlm/Mb+ Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
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MP:0002652 | thin myocardial wall | "thinly developed cardiac muscle layers" [il:Ira Lu , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Pdx1tm1Ted/Pdx1+ Genetic Background: involves: 129P2/OlaHsd
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MP:0003022 | increased coronary flow rate | "elevated rate of blood flow in the blood vessels supplying the heart" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
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Allelic Composition: Col1a1tm1.1Jcm/Col1a1+ Genetic Background: either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1)
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MP:0003081 | abnormal soleus morphology | "anomaly in the the superficial flat broad muscle of the calf that is responsible for plantar flexion of the foot" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, smb:Susan M. Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Prnptm1Cwe/Prnptm1Cwe,Tg(Prnp)c35Cwe/0 Genetic Background: Not Specified
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MP:0003646 | muscle fatigue | "increased muscle exhaustion or increased susceptibility to muscle exhaustion" [J:96306] |
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Allelic Composition: Prnptm1Cwe/Prnptm1Cwe,Tg(Prnp)c35Cwe/0 Genetic Background: Not Specified
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MP:0003957 | abnormal nitric oxide homeostasis | "anomaly in the state of equilibrium in the body of nitric oxide, a free radical gas and a potent vasodilator" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mbtm1Wlm/Mbtm1Wlm Genetic Background: B6.Cg-Mbtm1Wlm
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MP:0003984 | embryonic growth retardation | "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mbtm1Wlm/Mbtm1Wlm Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
Allelic Composition: Mbtm1Wlm/Mb+ Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
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MP:0005039 | hypoxia | "reduced concentration of O2 in the blood, alveoli or other tissues resulting in the decreased pressure of this component of body gases" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Prnptm1Cwe/Prnptm1Cwe,Tg(Prnp)c35Cwe/0 Genetic Background: Not Specified
Allelic Composition: Mbtm1Wlm/Mbtm1Wlm Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
Allelic Composition: Mbtm1Wlm/Mbtm1Wlm Genetic Background: B6.Cg-Mbtm1Wlm
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MP:0005266 | abnormal metabolism | "anomalous chemical and physical changes occurring in tissue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Prnptm1Cwe/Prnptm1Cwe,Tg(Prnp)c35Cwe/0 Genetic Background: Not Specified
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MP:0005312 | pericardial effusion | "escape of fluid from blood vessels or lymphatics into the fibrous sac surrounding the heart" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Mbtm1Wlm/Mbtm1Wlm Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
Allelic Composition: Mbtm1Wlm/Mb+ Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
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MP:0005329 | abnormal cardiac muscle morphology | "anomalous structure of the involuntary muscle comprising the myocardium " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Prnptm1Cwe/Prnptm1Cwe,Tg(Prnp)c35Cwe/0 Genetic Background: Not Specified
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MP:0005564 | increased hemoglobin content | "increase in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, RGD:Rat Genome Database submission] |
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Allelic Composition: Col1a1tm1.1Jcm/Col1a1+ Genetic Background: either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1)
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MP:0005598 | decreased ventricle muscle contractility | "reduced ability of the heart ventricle muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
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Allelic Composition: Mbtm1Wlm/Mbtm1Wlm Genetic Background: B6.Cg-Mbtm1Wlm
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MP:0005601 | increased angiogenesis | "enhanced process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network" [RGD:Rat Genome Database submission] |
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Allelic Composition: Prnptm1Cwe/Prnptm1Cwe,Tg(Prnp)c35Cwe/0 Genetic Background: Not Specified
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MP:0006138 | congestive heart failure | "the heart is unable to adequately pump blood throughout the body" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Mbtm1Wlm/Mbtm1Wlm Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
Allelic Composition: Mbtm1Wlm/Mb+ Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
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MP:0008788 | abnormal fetal cardiomyocyte morphology | "any structural anomaly of fetal and neonatal heart cells that undergo proliferation and are not yet terminally differentiated into binucleate or multinucleate cardiac myocytes" [PMID:17429040] |
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Allelic Composition: Mbtm1Wlm/Mbtm1Wlm Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
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MP:0009409 | abnormal skeletal muscle fiber type ratio | "deviation from the standard ratios of fiber types in a given skeletal muscle compared to control samples" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Prnptm1Cwe/Prnptm1Cwe,Tg(Prnp)c35Cwe/0 Genetic Background: Not Specified
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MP:0011108 | partial embryonic lethality during organogenesis | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: Mbtm1Wlm/Mbtm1Wlm Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
Allelic Composition: Mbtm1Wlm/Mb+ Genetic Background: either: (involves: 129/Sv) or (involves: C57BL/6)
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MP:0020330 | increased capillary density | "increase in the number of capillaries in a given cross-sectional area of a tissue" [ORCID: orcid.org/0000-0003-4606-0597, PMID:20705734] |
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Allelic Composition: Col1a1tm1.1Jcm/Col1a1+ Genetic Background: either: (involves: 129X1/SvJ * C3H/HeJ) or (involves: 129X1/SvJ * CD-1)
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