ENSMUSG00000018930


Mus musculus

Features
Gene ID: ENSMUSG00000018930
  
Biological name :Ccl4
  
Synonyms : Ccl4 / C-C motif chemokine 4 / P14097
  
Possible biological names infered from orthology : CCL4L2 / C-C motif chemokine ligand 4 / C-C motif chemokine ligand 4 like 2 / P13236 / Q8NHW4
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: C
Gene start: 83662584
Gene end: 83664683
  
Corresponding Affymetrix probe sets: 10379721 (MoGene1.0st)   1421578_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019074
NCBI entrez gene - 20303     See in Manteia.
MGI - MGI:98261
RefSeq - XM_011248832
RefSeq - NM_013652
RefSeq Peptide - NP_038680
swissprot - P14097
swissprot - Q5QNV9
Ensembl - ENSMUSG00000018930
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccl35.1ENSDARG00000103466Danio rerio
 ccl35.2ENSDARG00000070378Danio rerio
 ENSGALG00000043065Gallus gallus
 ENSGALG00000041079Gallus gallus
 ENSGALG00000014585Gallus gallus
 CCAH221ENSGALG00000027051Gallus gallus
 CCL4ENSGALG00000032717Gallus gallus
 CCL4ENSGALG00000034478Gallus gallus
 CCL4ENSG00000275302Homo sapiens
 CCL4L2ENSG00000276070Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ccl3 / P10855 / C-C motif chemokine 3 / CCL18* / P55774* / CCL3L1* / CCL3L3* / P10147* / P16619* / C-C motif chemokine ligand 3* / C-C motif chemokine ligand 18* / C-C motif chemokine liga...ENSMUSG0000000098260
Ccl5 / P30882 / C-C motif chemokine 5 / P13501* / C-C motif chemokine ligand 5*ENSMUSG0000003504250
Ccl26 / chemokine (C-C motif) ligand 26 / Q9Y258* / C-C motif chemokine ligand 26*ENSMUSG0000007046427


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0009636 response to toxic substance ISO
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0035690 cellular response to drug IDA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0043922 negative regulation by host of viral transcription ISO
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0050850 positive regulation of calcium-mediated signaling ISO
 biological_processGO:0051928 positive regulation of calcium ion transport ISO
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 biological_processGO:2000503 positive regulation of natural killer cell chemotaxis ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008009 chemokine activity IBA
 molecular_functionGO:0031726 CCR1 chemokine receptor binding ISO
 molecular_functionGO:0031730 CCR5 chemokine receptor binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0048020 CCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025804 Ccr1 / P51675 / C-C chemokine receptor type 1 / P32246* / C-C motif chemokine receptor 1*  / complex
 ENSMUSG00000064039 Ccr1l1 / P51676 / C-C chemokine receptor 1-like protein 1 / CCR1* / P32246* / C-C motif chemokine receptor 1*  / complex
 ENSMUSG00000079227 Ccr5 / P51682 / C-C chemokine receptor type 5 / P51681* / C-C motif chemokine receptor 5 (gene/pseudogene)*  / complex






 

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