ENSMUSG00000020100


Mus musculus

Features
Gene ID: ENSMUSG00000020100
  
Biological name :Slc29a3
  
Synonyms : Equilibrative nucleoside transporter 3 / Q99P65 / Slc29a3
  
Possible biological names infered from orthology : Q9BZD2 / solute carrier family 29 member 3
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: B4
Gene start: 60712072
Gene end: 60752794
  
Corresponding Affymetrix probe sets: 10369379 (MoGene1.0st)   1451013_at (Mouse Genome 430 2.0 Array)   1455731_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112685
Ensembl peptide - ENSMUSP00000119716
Ensembl peptide - ENSMUSP00000112426
NCBI entrez gene - 71279     See in Manteia.
MGI - MGI:1918529
RefSeq - XM_006514118
RefSeq - XM_006514119
RefSeq - NM_023596
RefSeq Peptide - NP_076085
swissprot - Q99P65
swissprot - D6RI95
swissprot - D3YWS9
Ensembl - ENSMUSG00000020100
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc29a3ENSDARG00000077828Danio rerio
 Q9BZD2ENSG00000198246Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9JIM1 / Slc29a1 / solute carrier family 29 (nucleoside transporters), member 1 / Q99808* / solute carrier family 29 member 1 (Augustine blood group)*ENSMUSG0000002394229
Q61672 / Slc29a2 / Equilibrative nucleoside transporter 2 / Q14542* / solute carrier family 29 member 2*ENSMUSG0000002489128
Q8R139 / Slc29a4 / Equilibrative nucleoside transporter 4 / Q7RTT9* / solute carrier family 29 member 4*ENSMUSG0000005082223


Protein motifs (from Interpro)
Interpro ID Name
 IPR002259  Equilibrative nucleoside transporter
 IPR030193  Equilibrative nucleoside transporter 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015858 nucleoside transport IEA
 biological_processGO:1901642 nucleoside transmembrane transport IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0005337 nucleoside transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000240 extramedullary hematopoiesis "formation and development of blood cells outside the bone marrow, e.g., in the spleen, liver, or lymph nodes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

 MP:0000691 enlarged spleen "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

 MP:0000702 enlarged lymph nodes "lymph nodes of increased size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

 MP:0002446 abnormal macrophage morphology "anomalous structure, number, or composition of the large mononuclear phagocytic cells found in most tissues of the body" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

 MP:0002451 abnormal macrophage physiology "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

 MP:0003172 abnormal lysosome physiology "ability of lysosomes to produce enzymes necessary for digestion of exogenous material is impaired" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

 MP:0005425 increased macrophage count "greater than the normal numbers of macrophages" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:73418]
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Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

 MP:0009321 histiocytic sarcoma 
Show

Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

 MP:0009788 increased susceptibility to bacterial infection induced morbidity/mortality "increased likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

 MP:0010373 myeloid hyperplasia "greater than normal number of nucleated cells of the myeloid lineage (a monocyte, granulocyte, or mast cell), found in blood or other tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

 MP:0011080 increased macrophage apoptosis "greater incidence of cell death in macrophages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc/Tyrc-13J
Genetic Background: (C57BL/6J x SJL/J)F1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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