ENSMUSG00000020109


Mus musculus

Features
Gene ID: ENSMUSG00000020109
  
Biological name :Dnajb12
  
Synonyms : Dnajb12 / DnaJ homolog subfamily B member 12 / Q9QYI4
  
Possible biological names infered from orthology : DnaJ heat shock protein family (Hsp40) member B12 / Q9NXW2
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: B4
Gene start: 59879556
Gene end: 59899302
  
Corresponding Affymetrix probe sets: 10363392 (MoGene1.0st)   1421032_a_at (Mouse Genome 430 2.0 Array)   1435886_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118088
Ensembl peptide - ENSMUSP00000122056
Ensembl peptide - ENSMUSP00000020309
Ensembl peptide - ENSMUSP00000116244
Ensembl peptide - ENSMUSP00000116577
NCBI entrez gene - 56709     See in Manteia.
MGI - MGI:1931881
RefSeq - NM_019965
RefSeq Peptide - NP_064349
swissprot - D6RHR9
swissprot - Q8C4C9
swissprot - Q9QYI4
Ensembl - ENSMUSG00000020109
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnajb12aENSDARG00000039363Danio rerio
 dnajb12bENSDARG00000087473Danio rerio
 DNAJB12ENSGALG00000034104Gallus gallus
 Q9NXW2ENSG00000148719Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q149L6 / Dnajb14 / DnaJ homolog subfamily B member 14 / Q8TBM8* / DnaJ heat shock protein family (Hsp40) member B14*ENSMUSG0000007421251
Q9CZJ9 / Dnajc18 / DnaJ homolog subfamily C member 18 / Q9H819* / DnaJ heat shock protein family (Hsp40) member C18*ENSMUSG0000002435037
Dnajc5 / P60904 / DnaJ homolog subfamily C member 5 / Q9H3Z4* / DnaJ heat shock protein family (Hsp40) member C5*ENSMUSG0000000082615
Q9CQ94 / Dnajc5b / DnaJ homolog subfamily C member 5B / Q9UF47* / DnaJ heat shock protein family (Hsp40) member C5 beta*ENSMUSG0000002760614
Dnajc5g / dnaJ homolog subfamily C member 5G isoform 2 / Q8N7S2* / DnaJ heat shock protein family (Hsp40) member C5 gamma*ENSMUSG0000005385613


Protein motifs (from Interpro)
Interpro ID Name
 IPR001623  DnaJ domain
 IPR015399  Domain of unknown function DUF1977, DnaJ-like
 IPR018253  DnaJ domain, conserved site
 IPR036869  Chaperone J-domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0034622 cellular protein-containing complex assembly ISS
 biological_processGO:0036503 ERAD pathway ISS
 biological_processGO:0051085 chaperone cofactor-dependent protein refolding ISS
 biological_processGO:0071218 cellular response to misfolded protein ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane ISS
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0030544 Hsp70 protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0009141 increased prepulse inhibition "increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Atp13a2tm1.2Wtd/Atp13a2tm1.2Wtd,Tg(Prnp-SNCA*A53T)83Vle/0
Genetic Background: involves: 129 * C3H * C57BL/6

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT2)Thl/0,Picalmtm1.1Tmae/Picalmtm1.1Tmae
Genetic Background: involves: 129 * C57BL/6 * SJL

 MP:0011396 abnormal sleep behavior "any anomaly in the actions, reactions, or performance of an organism during a periodic, readily reversible state of reduced awareness and metabolic activity" [MGI:smb]
Show

Allelic Composition: Atp13a2tm1.2Wtd/Atp13a2tm1.2Wtd,Tg(Prnp-SNCA*A53T)83Vle/0
Genetic Background: involves: 129 * C3H * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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