ENSMUSG00000020375


Mus musculus

Features
Gene ID: ENSMUSG00000020375
  
Biological name :Rufy1
  
Synonyms : Q8BIJ7 / Rufy1 / RUN and FYVE domain-containing protein 1
  
Possible biological names infered from orthology : Q96T51 / RUN and FYVE domain containing 1
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B1.3
Gene start: 50389286
Gene end: 50431125
  
Corresponding Affymetrix probe sets: 10385616 (MoGene1.0st)   1434131_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020643
NCBI entrez gene - 216724     See in Manteia.
MGI - MGI:2429762
RefSeq - XM_017314443
RefSeq - NM_172557
RefSeq - XM_006532841
RefSeq Peptide - NP_766145
swissprot - Q8BIJ7
Ensembl - ENSMUSG00000020375
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rufy1ENSDARG00000078685Danio rerio
 RUFY1ENSGALG00000029706Gallus gallus
 RUFY1ENSG00000176783Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rufy2 / Q8R4C2 / RUN and FYVE domain-containing 2 / Q8WXA3*ENSMUSG0000002007052
Rufy3 / Q9D394 / Protein RUFY3 / Q7L099* / RUN and FYVE domain containing 3*ENSMUSG0000002929144
O08576 / Rundc3a / RUN domain-containing protein 3A / Q59EK9* / RUN domain containing 3A*ENSMUSG0000000657515
Q6PDC0 / Rundc3b / RUN domain containing 3B / Q96NL0*ENSMUSG0000004057015


Protein motifs (from Interpro)
Interpro ID Name
 IPR000306  FYVE zinc finger
 IPR004012  RUN domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related
 IPR037213  RUN domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0015031 protein transport IDA
 biological_processGO:0030100 regulation of endocytosis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0008565 protein transporter activity IDA
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0042169 SH2 domain binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000017831 Rab5a / Q9CQD1 / Ras-related protein Rab-5A / P20339* / RAB5A, member RAS oncogene family*  / complex / reaction
 ENSMUSG00000026878 Rab14 / Q91V41 / RAB14, member RAS oncogene family / P61106*  / complex / reaction
 ENSMUSG00000019478 Rab4a / P56371 / Ras-related protein Rab-4A / P20338* / RAB4A, member RAS oncogene family*  / complex / reaction
 ENSMUSG00000031377 Bmx / P97504 / Cytoplasmic tyrosine-protein kinase BMX / P51813* / BMX non-receptor tyrosine kinase*  / reaction






 

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