ENSMUSG00000020627


Mus musculus

Features
Gene ID: ENSMUSG00000020627
  
Biological name :Klhl29
  
Synonyms : Kelch-like protein 29 / Klhl29 / Q80T74
  
Possible biological names infered from orthology : kelch like family member 29 / Q96CT2
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: A1.1
Gene start: 5077472
Gene end: 5375682
  
Corresponding Affymetrix probe sets: 10399337 (MoGene1.0st)   1434639_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151284
Ensembl peptide - ENSMUSP00000020958
NCBI entrez gene - 208439     See in Manteia.
MGI - MGI:2683857
RefSeq - NM_001164493
RefSeq Peptide - NP_001157965
swissprot - A0A1W2P6N5
swissprot - Q80T74
Ensembl - ENSMUSG00000020627
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klhl29ENSDARG00000087688Danio rerio
 zmp:0000000619ENSDARG00000043799Danio rerio
 KLHL29ENSGALG00000016495Gallus gallus
 KLHL29ENSG00000119771Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Klhl24 / Q8BRG6 / Kelch-like protein 24 / Q6TFL4* / kelch like family member 24*ENSMUSG0000006290124
Klhl38 / Q8BSF5 / Kelch-like protein 38 / Q2WGJ6* / kelch like family member 38*ENSMUSG0000002235721
Klhl21 / Q3U410 / Kelch-like protein 21 / Q9UJP4* / kelch like family member 21*ENSMUSG0000007370021
Klhl23 / Q6GQU2 / Kelch-like protein 23 / Q8NBE8* / kelch like family member 23*ENSMUSG0000004215520
Klhl30 / Q8C3F7 / Kelch-like protein 30 / Q0D2K2* / kelch like family member 30*ENSMUSG0000002630819
Klhl35 / Q9CZ49 / Kelch-like protein 35 / Q6PF15* / kelch like family member 35*ENSMUSG0000003529819
Enc1 / O35709 / Ectoderm-neural cortex protein 1 / O14682* / ectodermal-neural cortex 1*ENSMUSG0000004177319
Klhl6 / Q6V595 / Kelch-like protein 6 / Q8WZ60* / kelch like family member 6*ENSMUSG0000004300819
Klhl25 / Q8R2P1 / Kelch-like protein 25 / Q9H0H3* / kelch like family member 25*ENSMUSG0000005565219
Kbtbd2 / kelch repeat and BTB domain containing 2 / Q8IY47*ENSMUSG0000005948616
Klhl40 / kelch like family member 40 / Q2TBA0*ENSMUSG0000007400116
Kbtbd3 / Q8BHI4 / Kelch repeat and BTB domain-containing protein 3 / Q8NAB2* / kelch repeat and BTB domain containing 3*ENSMUSG0000002589315
Kbtbd8 / Q3UQV5 / Kelch repeat and BTB domain-containing protein 8 / Q8NFY9* / kelch repeat and BTB domain containing 8*ENSMUSG0000003003115
Q9D618 / Kbtbd12 / Kelch repeat and BTB domain-containing protein 12 / Q3ZCT8* / kelch repeat and BTB domain containing 12*ENSMUSG0000003318215
Kbtbd7 / Q86V97* / Q8WVZ9* / KBTBD6* / kelch repeat and BTB domain containing 6* / kelch repeat and BTB domain containing 7*ENSMUSG0000004388115
A2AUC9 / Klhl41 / Kelch-like protein 41 / O60662* / kelch like family member 41*ENSMUSG0000007530715
Kbtbd6 / uncharacterized protein LOC432879 / Q86V97* / Q8WVZ9* / KBTBD7* / kelch repeat and BTB domain containing 6* / kelch repeat and BTB domain containing 7*ENSMUSG0000007550211


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002626 increased heart rate "greater than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Kdm8tm1b(EUCOMM)Wtsi/Kdm8tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kdm8tm1b(EUCOMM)Wtsi/Ics

 MP:0003921 abnormal left ventricle morphology "structural anomaly of the left lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Kdm8tm1b(EUCOMM)Wtsi/Kdm8tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kdm8tm1b(EUCOMM)Wtsi/Ics

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kdm8tm1b(EUCOMM)Wtsi/Kdm8tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kdm8tm1b(EUCOMM)Wtsi/Ics

 MP:0005599 increased cardiac muscle contractility "greater than the normal ability of the heart muscle to shorten or to develop increased tension " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Kdm8tm1b(EUCOMM)Wtsi/Kdm8tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kdm8tm1b(EUCOMM)Wtsi/Ics

 MP:0009141 increased prepulse inhibition "increase in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kdm8tm1b(EUCOMM)Wtsi/Kdm8tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kdm8tm1b(EUCOMM)Wtsi/Ics

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Kdm8tm1b(EUCOMM)Wtsi/Kdm8tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kdm8tm1b(EUCOMM)Wtsi/Ics

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
Show

Allelic Composition: Kdm8tm1b(EUCOMM)Wtsi/Kdm8tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Kdm8tm1b(EUCOMM)Wtsi/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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