Manteia

ENSMUSG00000021200

Mus musculus

Features

Gene ID:	ENSMUSG00000021200

Biological name :	Asb2

Synonyms :	Ankyrin repeat and SOCS box protein 2 / Asb2 / Q8K0L0

Possible biological names infered from orthology :	ankyrin repeat and SOCS box containing 2 / Q96Q27

Species:	Mus musculus

Chr. number:	12
Strand:	-1
Band:	E
Gene start:	103321142
Gene end:	103356001

Corresponding Affymetrix probe sets:	10402325 (MoGene1.0st) 1428444_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000021617 Ensembl peptide - ENSMUSP00000117595 NCBI entrez gene - 65256 See in Manteia. MGI - MGI:1929743 RefSeq - NM_023049 RefSeq Peptide - NP_075536 swissprot - Q8K0L0 Ensembl - ENSMUSG00000021200

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Asb14 / ankyrin repeat and SOCS box containing 14 / A6NK59*	ENSMUSG00000021898	32
Asb15 / Q8VHS6 / Ankyrin repeat and SOCS box protein 15 / Q8WXK1* / ankyrin repeat and SOCS box containing 15*	ENSMUSG00000029685	29
Asb3 / Q9WV72 / Ankyrin repeat and SOCS box protein 3 / Q9Y575* / GPR75-ASB3* / GPR75-ASB3 readthrough* / ankyrin repeat and SOCS box containing 3*	ENSMUSG00000020305	22
Asb1 / Q9WV74 / Ankyrin repeat and SOCS box protein 1 / Q9Y576* / ankyrin repeat and SOCS box containing 1*	ENSMUSG00000026311	14
Asb5 / Q9D1A4 / Ankyrin repeat and SOCS box protein 5 / Q8WWX0* / ankyrin repeat and SOCS box containing 5*	ENSMUSG00000031519	14
Asb7 / Q91ZU0 / Ankyrin repeat and SOCS box protein 7 / Q9H672* / ankyrin repeat and SOCS box containing 7*	ENSMUSG00000030509	13
Asb9 / Q91ZT8 / Ankyrin repeat and SOCS box protein 9 / Q96DX5* / ankyrin repeat and SOCS box containing 9*	ENSMUSG00000031384	13
Asb12 / Q9D738 / Ankyrin repeat and SOCS box protein 12 / Q8WXK4* / ankyrin repeat and SOCS box containing 12*	ENSMUSG00000031204	12
Asb11 / Q9CQ31 / Ankyrin repeat and SOCS box protein 11 / Q8WXH4* / ankyrin repeat and SOCS box containing 11*	ENSMUSG00000031382	12
Asb13 / Q8VBX0 / Ankyrin repeat and SOCS box protein 13 / Q8WXK3* / ankyrin repeat and SOCS box containing 13*	ENSMUSG00000033781	12

Protein motifs (from Interpro)

Interpro ID	Name
IPR001496	SOCS box domain
IPR002110	Ankyrin repeat
IPR003903	Ubiquitin interacting motif
IPR020683	Ankyrin repeat-containing domain
IPR036036	SOCS box-like domain superfamily
IPR036770	Ankyrin repeat-containing domain superfamily
IPR037330	Ankyrin repeat and SOCS box protein 2, SOCS box domain

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000209	protein polyubiquitination	IDA
biological_process	GO:0016567	protein ubiquitination	ISO
biological_process	GO:0035556	intracellular signal transduction	IEA
biological_process	GO:0035914	skeletal muscle cell differentiation	IMP
biological_process	GO:0045445	myoblast differentiation	IMP
cellular_component	GO:0000151	ubiquitin ligase complex	ISO
cellular_component	GO:0031466	Cul5-RING ubiquitin ligase complex	IDA
molecular_function	GO:0005515	protein binding	IEA
molecular_function	GO:0061630	ubiquitin protein ligase activity	ISO

Pathways (from Reactome)

Pathway description

Neddylation

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002376	abnormal dendritic cell physiology	"failure or atypical function of the immunocompetent cells of the lymphoid and hemopoietic systems and skin, which function to process antigens and present them to T cells, thus stimulating cellular immunity" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:85808]	Show Allelic Composition: Snca^tm1.1Koks/Snca⁺ Genetic Background: either: B6.129P2-Snca^tm1.1Koks or (involves: 129P2/OlaHsd * C57BL/6)

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr