ENSMUSG00000021241


Mus musculus

Features
Gene ID: ENSMUSG00000021241
  
Biological name :Isca2
  
Synonyms : Iron-sulfur cluster assembly 2 homolog, mitochondrial / Isca2 / Q9DCB8
  
Possible biological names infered from orthology : iron-sulfur cluster assembly 2 / Q86U28
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: D1
Gene start: 84773251
Gene end: 84775088
  
Corresponding Affymetrix probe sets: 10397267 (MoGene1.0st)   1424154_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021667
Ensembl peptide - ENSMUSP00000152880
Ensembl peptide - ENSMUSP00000152679
Ensembl peptide - ENSMUSP00000152379
NCBI entrez gene - 74316     See in Manteia.
MGI - MGI:1921566
RefSeq - XM_006516296
RefSeq - XM_006516298
RefSeq - XM_006516297
RefSeq - NM_028863
RefSeq Peptide - NP_083139
swissprot - Q9DCB8
swissprot - A0A1Y7VM99
swissprot - A0A1Y7VK19
swissprot - A0A1Y7VLA3
Ensembl - ENSMUSG00000021241
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 isca2ENSDARG00000038154Danio rerio
 ISCA2ENSGALG00000020417Gallus gallus
 ISCA2ENSG00000165898Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000361  FeS cluster biogenesis
 IPR016092  FeS cluster insertion protein
 IPR017870  FeS cluster insertion, C-terminal, conserved site
 IPR035903  HesB-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016226 iron-sulfur cluster assembly IBA
 biological_processGO:0051604 protein maturation IBA
 biological_processGO:0097428 protein maturation by iron-sulfur cluster transfer IEA
 cellular_componentGO:0005739 mitochondrion IDA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005506 iron ion binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051537 2 iron, 2 sulfur cluster binding IBA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IBA


Pathways (from Reactome)
Pathway description
Mitochondrial iron-sulfur cluster biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000021102 Glrx5 / Q80Y14 / Glutaredoxin-related protein 5, mitochondrial / Q86SX6* / glutaredoxin 5*  / reaction
 ENSMUSG00000044792 Isca1 / Q9D924 / Iron-sulfur cluster assembly 1 homolog, mitochondrial / Q9BUE6* / iron-sulfur cluster assembly 1*  / complex






 

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