ENSMUSG00000021872


Mus musculus

Features
Gene ID: ENSMUSG00000021872
  
Biological name :Rnase10
  
Synonyms : ribonuclease, RNase A family, 10 (non-active) / Rnase10
  
Possible biological names infered from orthology : Q5GAN6 / ribonuclease A family member 10 (inactive)
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C1
Gene start: 51007751
Gene end: 51010758
  
Corresponding Affymetrix probe sets: 10414533 (MoGene1.0st)   1453215_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000131065
Ensembl peptide - ENSMUSP00000022424
NCBI entrez gene - 75019     See in Manteia.
MGI - MGI:1922269
RefSeq - NM_029145
RefSeq - NM_001162863
RefSeq - XM_006519639
RefSeq Peptide - NP_001156335
RefSeq Peptide - NP_083421
swissprot - G3UWD1
swissprot - E9QPU5
Ensembl - ENSMUSG00000021872
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5GAN6ENSG00000182545Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001427  Pancreatic ribonuclease
 IPR023412  Ribonuclease A-domain
 IPR029742  Inactive ribonuclease-like protein 10
 IPR036816  Ribonuclease A-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003676 nucleic acid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Nf2tm2Gth/Nf2tm2Gth
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0001148 enlarged testes "increased size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:63229]
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd
Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp

 MP:0001875 testis inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the testis" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002631 abnormal epididymis morphology "malformation of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002660 abnormal caput "anomalous structure of the head of the epididymis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003205 testicular atrophy "wasting of the male reproductive glands resulting in reduced size" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003698 abnormal male reproductive system physiology "anomaly in the function of the male organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd
Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp

 MP:0004933 abnormal epididymis epithelium morphology "any structural anomaly of the layer of secretory cells which lines the epididymis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004934 epididymis epithelium degeneration "pathological deterioration of the layer of secretory cells which lines the epididymis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0009198 abnormal male genitalia morphology "any structural anomaly of the masculine organs of reproduction or generation, external or internal" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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