ENSMUSG00000021893


Mus musculus

Features
Gene ID: ENSMUSG00000021893
  
Biological name :Capn7
  
Synonyms : Calpain-7 / Capn7 / Q9R1S8
  
Possible biological names infered from orthology : Q9Y6W3
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: B
Gene start: 31336638
Gene end: 31371986
  
Corresponding Affymetrix probe sets: 10413771 (MoGene1.0st)   1423096_at (Mouse Genome 430 2.0 Array)   1423097_s_at (Mouse Genome 430 2.0 Array)   1423098_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022451
Ensembl peptide - ENSMUSP00000118596
Ensembl peptide - ENSMUSP00000119214
NCBI entrez gene - 12339     See in Manteia.
MGI - MGI:1338030
RefSeq - XM_017315830
RefSeq - NM_009796
RefSeq - XM_006518502
RefSeq - XM_017315829
RefSeq Peptide - NP_033926
swissprot - F2Z3X0
swissprot - Q9R1S8
Ensembl - ENSMUSG00000021893
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 capn7ENSDARG00000102987Danio rerio
 CAPN7ENSGALG00000041731Gallus gallus
 CAPN7ENSG00000131375Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Capn15 / Q9JLG8 / Mus musculus calpain 15 (Capn15), transcript variant 1, mRNA. / O75808* / calpain 15*ENSMUSG0000003732615
Capn10 / Q9ESK3 / Calpain-10 / Q9HC96*ENSMUSG0000002627012


Protein motifs (from Interpro)
Interpro ID Name
 IPR001300  Peptidase C2, calpain, catalytic domain
 IPR007330  MIT
 IPR022682  Peptidase C2, calpain, large subunit, domain III
 IPR022683  Peptidase C2, calpain, domain III
 IPR022684  Peptidase C2, calpain family
 IPR036181  MIT domain superfamily
 IPR036213  Calpain large subunit, domain III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0010634 positive regulation of epithelial cell migration IEA
 biological_processGO:0097264 self proteolysis IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0090541 MIT domain binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Cacng4tm1Dgen/Cacng4tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001973 increased thermal nociceptive threshold "a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]
Show

Allelic Composition: Cacng4tm1Dgen/Cacng4tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Cacng4tm1Dgen/Cacng4tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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