ENSMUSG00000022245


Mus musculus

Features
Gene ID: ENSMUSG00000022245
  
Biological name :Skor1
  
Synonyms : Q8BX46 / SKI family transcriptional corepressor 1 / Skor1
  
Possible biological names infered from orthology : P84550
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: B
Gene start: 63138170
Gene end: 63148961
  
Corresponding Affymetrix probe sets: 10594340 (MoGene1.0st)   1437880_at (Mouse Genome 430 2.0 Array)   1460100_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000055037
Ensembl peptide - ENSMUSP00000112312
Ensembl peptide - ENSMUSP00000113924
NCBI entrez gene - 207667     See in Manteia.
MGI - MGI:2443473
RefSeq - XM_006510910
RefSeq - NM_001163755
RefSeq - NM_001163757
RefSeq - NM_001163758
RefSeq - NM_172446
RefSeq - XM_006510909
RefSeq Peptide - NP_001157229
RefSeq Peptide - NP_001157230
RefSeq Peptide - NP_766034
RefSeq Peptide - NP_001157227
swissprot - Q8BX46
swissprot - D3YX64
Ensembl - ENSMUSG00000022245
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q1LXZ9ENSDARG00000062448Danio rerio
 skor1aENSDARG00000069030Danio rerio
 SKOR1ENSGALG00000029521Gallus gallus
 SKOR1ENSG00000188779Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Skor2 / A7M7C7 / SKI family transcriptional corepressor 2 / Q2VWA4*ENSMUSG0000009151941
Ski / SKI proto-oncogene / P12755*ENSMUSG0000002905017
Skil / Q60665 / SKI-like / P12757* / SKI like proto-oncogene*ENSMUSG0000002766014


Protein motifs (from Interpro)
Interpro ID Name
 IPR003380  SKI/SNO/DAC domain
 IPR009061  Putative DNA-binding domain superfamily
 IPR010919  SAND-like domain superfamily
 IPR014890  c-SKI SMAD4-binding domain
 IPR023216  Transcription regulator SKI/SnoN
 IPR028762  Ski family transcriptional corepressor 1
 IPR037000  Ski-like, DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway IBA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IBA
 biological_processGO:0045596 negative regulation of cell differentiation IBA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0048666 neuron development IBA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046332 SMAD binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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