ENSMUSG00000022303


Mus musculus

Features
Gene ID: ENSMUSG00000022303
  
Biological name :Dcstamp
  
Synonyms : Dcstamp / Dendritic cell-specific transmembrane protein / Q7TNJ0
  
Possible biological names infered from orthology : dendrocyte expressed seven transmembrane protein / Q9H295
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: B3.1
Gene start: 39745930
Gene end: 39760938
  
Corresponding Affymetrix probe sets: 10423894 (MoGene1.0st)   1431970_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022913
Ensembl peptide - ENSMUSP00000153957
Ensembl peptide - ENSMUSP00000154362
Ensembl peptide - ENSMUSP00000154397
Ensembl peptide - ENSMUSP00000154564
NCBI entrez gene - 75766     See in Manteia.
MGI - MGI:1923016
RefSeq - XM_006521519
RefSeq - NM_001289506
RefSeq - NM_001289508
RefSeq - NM_001289512
RefSeq - NM_001289513
RefSeq - NM_029422
RefSeq Peptide - NP_001276437
RefSeq Peptide - NP_001276441
RefSeq Peptide - NP_001276442
RefSeq Peptide - NP_083698
RefSeq Peptide - NP_001276435
swissprot - Q7TNJ0
Ensembl - ENSMUSG00000022303
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DCSTAMPENSGALG00000033520Gallus gallus
 Q9H295ENSG00000164935Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR012858  Dendritic cell-specific transmembrane protein-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030308 negative regulation of cell growth IDA
 biological_processGO:0030316 osteoclast differentiation IMP
 biological_processGO:0034241 positive regulation of macrophage fusion IMP
 biological_processGO:0036006 cellular response to macrophage colony-stimulating factor stimulus IDA
 biological_processGO:0043011 myeloid dendritic cell differentiation IDA
 biological_processGO:0045657 positive regulation of monocyte differentiation IDA
 biological_processGO:0045780 positive regulation of bone resorption IMP
 biological_processGO:0061025 membrane fusion IMP
 biological_processGO:0071353 cellular response to interleukin-4 IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IDA
 biological_processGO:0072675 osteoclast fusion IMP
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0010008 endosome membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000062 increased bone density "increased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]
Show

Allelic Composition: Hspg2tm1Ref/Hspg2tm1Ref,Mmp9tm1Tvu/Mmp9tm1Tvu
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

 MP:0000067 osteopetrosis "excessive formation of dense trabecular bone and excessive calcified cartilage formation; may lead to anemia and extramedullary hematopoiesis " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Hspg2tm1Ref/Hspg2tm1Ref,Mmp9tm1Tvu/Mmp9tm1Tvu
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

 MP:0001541 abnormal osteoclast function "reduced ability or inability of osteoclasts to absorb and remove osseous tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795]
Show

Allelic Composition: Hspg2tm1Ref/Hspg2tm1Ref,Mmp9tm1Tvu/Mmp9tm1Tvu
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

 MP:0002451 abnormal macrophage physiology "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hspg2tm1Ref/Hspg2tm1Ref,Mmp9tm1Tvu/Mmp9tm1Tvu
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

 MP:0005605 increased bone mass "an increase in the total amount of bone tissue contained in the skeleton" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hspg2tm1Ref/Hspg2tm1Ref,Mmp9tm1Tvu/Mmp9tm1Tvu
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

 MP:0008396 abnormal osteoclast differentiation "atypical production of or inability to produce bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hspg2tm1Ref/Hspg2tm1Ref,Mmp9tm1Tvu/Mmp9tm1Tvu
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

 MP:0010872 increased trabecular bone mass "greater total amount of trabecular bone tissue contained in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hspg2tm1Ref/Hspg2tm1Ref,Mmp9tm1Tvu/Mmp9tm1Tvu
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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