ENSMUSG00000022412


Mus musculus
bindingMief1membranemitochondrialproteinfissionregulationmab-domaincellularresponsehypoxiatargetingmitochondrionouterintegralcomponentnucleotidegdpidenticaladp

Features
Gene ID: ENSMUSG00000022412
  
Biological name :Mief1
  
Synonyms : Mief1 / mitochondrial elongation factor 1 / Q8BGV8
  
Possible biological names infered from orthology : Q9NQG6
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: E1
Gene start: 80234018
Gene end: 80253371
  
Corresponding Affymetrix probe sets: 10425357 (MoGene1.0st)   1434712_at (Mouse Genome 430 2.0 Array)   1434713_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023048
Ensembl peptide - ENSMUSP00000129209
Ensembl peptide - ENSMUSP00000154748
Ensembl peptide - ENSMUSP00000154875
NCBI entrez gene - 239555     See in Manteia.
MGI - MGI:2146020
RefSeq - XM_006520948
RefSeq - NM_001357659
RefSeq - NM_178719
RefSeq - XM_006520946
RefSeq - XM_006520947
RefSeq Peptide - NP_001344588
RefSeq Peptide - NP_848834
swissprot - Q8BGV8
swissprot - B2RPW2
Ensembl - ENSMUSG00000022412
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mief1ENSDARG00000060991Danio rerio
 MIEF1ENSGALG00000012144Gallus gallus
 MIEF1ENSG00000100335Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mief2 / Q5NCS9 / Mitochondrial dynamics protein MID49 / Q96C03* / mitochondrial elongation factor 2*ENSMUSG0000001859941


Protein motifs (from Interpro)
Interpro ID Name
 IPR024810  Mab-21 domain


Gene Ontology (GO)
cellular component organizationresponse to stressresponse to chemicalcellular response to stimulusresponse to abiotic stimulusanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationresponse to stressresponse to chemicalcellular response to stimulusresponse to abiotic stimulusanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationresponse to stressresponse to chemicalcellular response to stimulusresponse to abiotic stimulusanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationresponse to stressresponse to chemicalcellular response to stimulusresponse to abiotic stimulusanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationresponse to stressresponse to chemicalcellular response to stimulusresponse to abiotic stimulusanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationresponse to stressresponse to chemicalcellular response to stimulusresponse to abiotic stimulusanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationresponse to stressresponse to chemicalcellular response to stimulusresponse to abiotic stimulusanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationresponse to stressresponse to chemicalcellular response to stimulusresponse to abiotic stimulusanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationresponse to stressresponse to chemicalcellular response to stimulusresponse to abiotic stimulusanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationcellular component organizationresponse to stressresponse to chemicalcellular response to stimulusresponse to abiotic stimulusanatomical structure developmentmacromolecule localizationestablishment of localizationcellular localizationcellular componcellular component organizationresponse to strresponse to stressresponse to cheresponse to chemicalcellular responcellular response to stimulusresponse to abiresponse to abiotic stimulusanatomical struanatomical structure developmentmacromolecule lmacromolecule localizationestablishment oestablishment of localizationcellular localicellular localization
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingprotein bindingion bindingcarbohydrate derivative bindingorganic cyclic compoundorganic cyclic compound bindingheterocyclic compound bheterocyclic compound bindingsmall molecule bindingsmall molecule bindingprotein bindingprotein bindingion bindingion bindingcarbohydrate derivativecarbohydrate derivative binding
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0000266 mitochondrial fission ISO
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:0090141 positive regulation of mitochondrial fission ISS
 biological_processGO:0090314 positive regulation of protein targeting to membrane ISS
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005741 mitochondrial outer membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019003 GDP binding ISO
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043531 ADP binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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