ENSMUSG00000022477


Mus musculus

Features
Gene ID: ENSMUSG00000022477
  
Biological name :Aco2
  
Synonyms : Aco2 / aconitase 2, mitochondrial / Q99KI0
  
Possible biological names infered from orthology : aconitase 2 / Q99798
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: E1
Gene start: 81872309
Gene end: 81915133
  
Corresponding Affymetrix probe sets: 10425611 (MoGene1.0st)   1436934_s_at (Mouse Genome 430 2.0 Array)   1451002_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000155818
Ensembl peptide - ENSMUSP00000023116
Ensembl peptide - ENSMUSP00000154821
Ensembl peptide - ENSMUSP00000154939
Ensembl peptide - ENSMUSP00000155234
NCBI entrez gene - 11429     See in Manteia.
MGI - MGI:87880
RefSeq - NM_080633
RefSeq Peptide - NP_542364
swissprot - Q99KI0
Ensembl - ENSMUSG00000022477
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aco2ENSDARG00000007294Danio rerio
 ACO2ENSGALG00000011950Gallus gallus
 ACO2ENSG00000100412Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000573  Aconitase A/isopropylmalate dehydratase small subunit, swivel domain
 IPR001030  Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain
 IPR006248  Aconitase, mitochondrial-like
 IPR015928  Aconitase/3-isopropylmalate dehydratase, swivel
 IPR015931  Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3
 IPR015932  Aconitase, domain 2
 IPR018136  Aconitase family, 4Fe-4S cluster binding site
 IPR036008  Aconitase, iron-sulfur domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IEA
 biological_processGO:0006099 tricarboxylic acid cycle ISO
 biological_processGO:0006101 citrate metabolic process IEA
 biological_processGO:0006102 isocitrate metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0035900 response to isolation stress IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0043209 myelin sheath IDA
 molecular_functionGO:0003994 aconitate hydratase activity ISO
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051538 3 iron, 4 sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Citric acid cycle (TCA cycle)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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