ENSMUSG00000022538


Mus musculus
bindingdomainLsg1gtpproteinhydrolasenuclearbodyactivitygtp-bindingorthogonalbundlesuperfamilyp-loopcontainingnucleosidetriphosphatecircularlypermutedcp-typeguaninenucleotide-bindinggtransportribosomebiogenesisexportnucleuscytoplasmendoplasmic

Features
Gene ID: ENSMUSG00000022538
  
Biological name :Lsg1
  
Synonyms : Large subunit GTPase 1 homolog / Lsg1 / Q3UM18
  
Possible biological names infered from orthology : large 60S subunit nuclear export GTPase 1 / Q9H089
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: B2
Gene start: 30560494
Gene end: 30587592
  
Corresponding Affymetrix probe sets: 10438959 (MoGene1.0st)   1437630_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115880
Ensembl peptide - ENSMUSP00000117960
Ensembl peptide - ENSMUSP00000112860
NCBI entrez gene - 224092     See in Manteia.
MGI - MGI:107236
RefSeq - NM_178069
RefSeq Peptide - NP_835170
swissprot - Q3UM18
swissprot - D6RFS1
swissprot - F7AMG0
Ensembl - ENSMUSG00000022538
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lsg1ENSDARG00000015352Danio rerio
 LSG1ENSGALG00000007058Gallus gallus
 LSG1ENSG00000041802Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gnl1 / P36916 / guanine nucleotide binding protein-like 1 / P36915* / G protein nucleolar 1 (putative)*ENSMUSG0000002442925


Protein motifs (from Interpro)
Interpro ID Name
 IPR006073  GTP binding domain
 IPR023179  GTP-binding protein, orthogonal bundle domain superfamily
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030378  Circularly permuted (CP)-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
macromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationmacromolecule localizationestablishment of localizationcellular component biogenesiscellular localizationmacromolecule localizationmacromolecule localizationestablishment of localizationestablishment of localizationcellular component biogenesiscellular component biogenesiscellular localizationcellular localization
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindinghydrolase activityion bindingcarbohydrate derivative bindingorganic cyclic compoundorganic cyclic compound bindingheterocyclic compound bheterocyclic compound bindingsmall molecule bindingsmall molecule bindinghydrolase activityhydrolase activityion bindingion bindingcarbohydrate derivativecarbohydrate derivative binding
cellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellorganellemembrane-enclosed lumencellcellorganelleorganellemembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0042254 ribosome biogenesis IBA
 biological_processGO:0051168 nuclear export IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0015030 Cajal body IEA
 cellular_componentGO:0016604 nuclear body IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding ISO
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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