ENSMUSG00000022750


Mus musculus

Features
Gene ID: ENSMUSG00000022750
  
Biological name :Klhl22
  
Synonyms : Klhl22 / Mus musculus kelch-like 22 (Klhl22), transcript variant 2, mRNA. / Q99JN2
  
Possible biological names infered from orthology : kelch like family member 22 / Q53GT1
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: A3
Gene start: 17759618
Gene end: 17793382
  
Corresponding Affymetrix probe sets: 10434094 (MoGene1.0st)   1426481_at (Mouse Genome 430 2.0 Array)   1430807_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119191
Ensembl peptide - ENSMUSP00000118696
Ensembl peptide - ENSMUSP00000122145
Ensembl peptide - ENSMUSP00000127227
Ensembl peptide - ENSMUSP00000112412
Ensembl peptide - ENSMUSP00000114115
NCBI entrez gene - 224023     See in Manteia.
MGI - MGI:1337995
RefSeq - XM_006522041
RefSeq - NM_001359068
RefSeq - NM_145479
RefSeq - XM_006522039
RefSeq - XM_006522040
RefSeq Peptide - NP_001345997
RefSeq Peptide - NP_663454
swissprot - H9KV05
swissprot - D3Z2R6
swissprot - Q99JN2
swissprot - D3Z7N9
swissprot - D3YZH5
Ensembl - ENSMUSG00000022750
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klhl22ENSDARG00000088807Danio rerio
 KLHL22ENSGALG00000006422Gallus gallus
 KLHL22ENSG00000099910Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Klhl36 / Q8R124 / Kelch-like protein 36 / Q8N4N3* / kelch like family member 36*ENSMUSG0000003182832
Klhl13 / Q80TF4 / Kelch-like protein 13 / Q9P2N7* / kelch like family member 13*ENSMUSG0000003678230
Klhl26 / Q8BGY4 / Kelch-like protein 26 / Q53HC5* / kelch like family member 26*ENSMUSG0000005570730
Klhl9 / Q6ZPT1 / Kelch-like protein 9 / Q9P2J3* / kelch like family member 9*ENSMUSG0000007092330
Klhl32 / kelch like family member 32 / Q96NJ5*ENSMUSG0000004038728
A2AAX3 / Klhl15 / Kelch-like protein 15 / Q96M94* / kelch like family member 15*ENSMUSG0000004392926
Klhl31 / kelch like family member 31 / Q9H511*ENSMUSG0000004493826
Klhl14 / Q69ZK5 / Kelch-like protein 14 / Q9P2G3* / kelch like family member 14*ENSMUSG0000004251425
Klhl34 / kelch like family member 34 / Q8N239*ENSMUSG0000004748525
Ipp / P28575 / Actin-binding protein IPP / Q9Y573* / intracisternal A particle-promoted polypeptide*ENSMUSG0000002869623
Klhl7 / Q8BUL5 / kelch-like 7 / Q8IXQ5* / kelch like family member 7*ENSMUSG0000002898623
Klhl33 / kelch like family member 33 / A6NCF5*ENSMUSG0000009079920
Q920Q8 / Ivns1abp / Influenza virus NS1A-binding protein homolog / Q9Y6Y0* / influenza virus NS1A binding protein*ENSMUSG0000002315019
Gan / Q8CA72 / Gigaxonin / Q9H2C0*ENSMUSG0000005255719


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR006652  Kelch repeat type 1
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR011705  BTB/Kelch-associated
 IPR015915  Kelch-type beta propeller
 IPR017096  BTB-kelch protein
 IPR030575  Kelch-like protein 22
 IPR037293  Galactose oxidase, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000070 mitotic sister chromatid segregation IEA
 biological_processGO:0006513 protein monoubiquitination IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007094 mitotic spindle assembly checkpoint IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0051301 cell division ISO
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005827 polar microtubule IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex ISO
 cellular_componentGO:0072686 mitotic spindle IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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