ENSMUSG00000022938


Mus musculus

Features
Gene ID: ENSMUSG00000022938
  
Biological name :Fam3b
  
Synonyms : Fam3b / Protein FAM3B / Q9D309
  
Possible biological names infered from orthology : family with sequence similarity 3 member B / P58499
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: C4
Gene start: 97471050
Gene end: 97504936
  
Corresponding Affymetrix probe sets: 10441244 (MoGene1.0st)   1425122_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000062006
NCBI entrez gene - 52793     See in Manteia.
MGI - MGI:1270150
RefSeq - NM_020622
RefSeq Peptide - NP_065647
swissprot - Q9D309
Ensembl - ENSMUSG00000022938
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FAM3BENSGALG00000016140Gallus gallus
 FAM3BENSG00000183844Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fam3c / Q91VU0 / Protein FAM3C / Q92520* / family with sequence similarity 3 member C*ENSMUSG0000002967233
Oit1 / P97805 / oncoprotein induced transcript 1 / FAM3D* / Q96BQ1* / family with sequence similarity 3 member D*ENSMUSG0000002174930
Fam3a / Q9D8T0 / Protein FAM3A / P98173* / family with sequence similarity 3 member A*ENSMUSG0000003139930


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030073 insulin secretion IEA
 cellular_componentGO:0005576 extracellular region NAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005641 nuclear envelope lumen ISO
 molecular_functionGO:0005125 cytokine activity NAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002078 abnormal glucose homeostasis "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gsk3atm1Dral/Gsk3atm1Dral,Gsk3btm1Dral/Gsk3btm1Dral,Gys1tm1.1Arte/Gys1tm1.1Arte
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0002079 increased circulating insulin level "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gsk3atm1Dral/Gsk3atm1Dral,Gsk3btm1Dral/Gsk3btm1Dral,Gys1tm1.1Arte/Gys1tm1.1Arte
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0003059 decreased insulin secretion "less than normal release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine - Medical Subject Headings, 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Gsk3atm1Dral/Gsk3atm1Dral,Gsk3btm1Dral/Gsk3btm1Dral,Gys1tm1.1Arte/Gys1tm1.1Arte
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0003839 abnormal insulin clearance "increase or decrease in the rate at which insulin is removed from the blood stream" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:99786]
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Allelic Composition: Gsk3atm1Dral/Gsk3atm1Dral,Gsk3btm1Dral/Gsk3btm1Dral,Gys1tm1.1Arte/Gys1tm1.1Arte
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gsk3atm1Dral/Gsk3atm1Dral,Gsk3btm1Dral/Gsk3btm1Dral,Gys1tm1.1Arte/Gys1tm1.1Arte
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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