ENSMUSG00000023011


Mus musculus

Features
Gene ID: ENSMUSG00000023011
  
Biological name :Faim2
  
Synonyms : Faim2 / Protein lifeguard 2 / Q8K097
  
Possible biological names infered from orthology : Fas apoptotic inhibitory molecule 2 / Q9BWQ8
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: F1
Gene start: 99497012
Gene end: 99528165
  
Corresponding Affymetrix probe sets: 10432492 (MoGene1.0st)   1429518_at (Mouse Genome 430 2.0 Array)   1455410_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023750
Ensembl peptide - ENSMUSP00000155195
NCBI entrez gene - 72393     See in Manteia.
MGI - MGI:1919643
RefSeq - XM_006521449
RefSeq - NM_001038658
RefSeq - NM_028224
RefSeq Peptide - NP_082500
RefSeq Peptide - NP_001033747
swissprot - Q8K097
Ensembl - ENSMUSG00000023011
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 faim2bENSDARG00000105362Danio rerio
 FAIM2ENSGALG00000031615Gallus gallus
 FAIM2ENSG00000135472Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tmbim1 / transmembrane BAX inhibitor motif containing 1 / Q969X1*ENSMUSG0000000630148
Grina / Q9ESF4 / Protein lifeguard 1 / Q7Z429* / glutamate ionotropic receptor NMDA type subunit associated protein 1*ENSMUSG0000002256439
Tmbim7 / transmembrane BAX inhibitor motif containing 7ENSMUSG0000001452929
Q9DA39 / Tmbim4 / transmembrane BAX inhibitor motif containing 4 / Q9HC24* / AC078927.1*ENSMUSG0000002022523


Protein motifs (from Interpro)
Interpro ID Name
 IPR006214  Bax inhibitor 1-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002931 response to ischemia IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007417 central nervous system development IEA
 biological_processGO:0021549 cerebellum development IMP
 biological_processGO:0021680 cerebellar Purkinje cell layer development IMP
 biological_processGO:0021681 cerebellar granular layer development IMP
 biological_processGO:0021702 cerebellar Purkinje cell differentiation IMP
 biological_processGO:0043523 regulation of neuron apoptotic process IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IMP
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway IMP
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
Show

Allelic Composition: Icam1tm1Bay/Icam1tm1Bay,Selptm1Bay/Selptm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Faim2tm1Dgen/Faim2+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Icam1tm1Bay/Icam1tm1Bay,Selptm1Bay/Selptm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002906 susceptibility to pharmacologically induced seizures "inability to withstand doses of pharmacological drugs that induce seizure activity in normal animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:69504]
Show

Allelic Composition: Icam1tm1Bay/Icam1tm1Bay,Selptm1Bay/Selptm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0003068 enlarged kidney "larger than average size of the kidney" [J:86005, pvb:Pierre Vanden Borre, Mouse Genome Informatics Curator]
Show

Allelic Composition: Icam1tm1Bay/Icam1tm1Bay,Selptm1Bay/Selptm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0003917 increased kidney weight "greater heft of the organs responsible for urine secretion" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Icam1tm1Bay/Icam1tm1Bay,Selptm1Bay/Selptm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0006060 increased cerebral infarction size "increased size of necrotic area of the cerebrum resulting from a sudden insufficiency of arterial or venous blood supply" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Itgaltm1.1Mshi/Itgaltm1.1Mshi
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr