ENSMUSG00000023140


Mus musculus

Features
Gene ID: ENSMUSG00000023140
  
Biological name :Reg2
  
Synonyms : Q08731 / Reg2 / regenerating islet-derived 2
  
Possible biological names infered from orthology : P05451 / P48304 / REG1A / REG1B / regenerating family member 1 alpha / regenerating family member 1 beta
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: C3
Gene start: 78395623
Gene end: 78408106
  
Corresponding Affymetrix probe sets: 10539194 (MoGene1.0st)   1416139_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000145184
Ensembl peptide - ENSMUSP00000023906
NCBI entrez gene - 19693     See in Manteia.
MGI - MGI:97896
RefSeq - NM_009043
RefSeq Peptide - NP_033069
swissprot - A0A0N4SVN9
swissprot - Q08731
swissprot - Q545J0
Ensembl - ENSMUSG00000023140
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 REG1AENSG00000115386Homo sapiens
 REG1BENSG00000172023Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Reg1 / P43137 / regenerating islet-derived 1 / REG1A* / REG1B* / P48304* / P05451* / regenerating family member 1 beta* / regenerating family member 1 alpha*ENSMUSG0000005965475
Reg3g / O09049 / regenerating islet-derived 3 gamma / REG3A* / Q6UW15* / Q06141* / regenerating family member 3 alpha* / regenerating family member 3 gamma*ENSMUSG0000003001740
Reg3d / regenerating islet-derived 3 delta / REG3A* / REG3G* / Q6UW15* / Q06141* / regenerating family member 3 alpha* / regenerating family member 3 gamma*ENSMUSG0000006834140
Reg3b / P35230 / Rerating islet-derived protein 3-beta Rerating islet-derived protein 3-beta 16.5 kDa form Rerating islet-derived protein 3-beta 15 kDa form / REG3G* / REG3A* / Q06141* / Q6...ENSMUSG0000007135640
Reg3a / O09037 / regenerating islet-derived 3 alpha / REG3G* / Q06141* / Q6UW15* / regenerating family member 3 alpha* / regenerating family member 3 gamma*ENSMUSG0000007951638
Reg4 / Q9D8G5 / Rerating islet-derived protein 4 / Q9BYZ8* / regenerating family member 4*ENSMUSG0000002787624


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001967 suckling behavior IMP
 biological_processGO:0042552 myelination IMP
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001076 abnormal hypoglossal nerve morphology "malformation or misprojection of motor axons to the tongue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:45302]
Show

Allelic Composition: Cidectm1Pli/Cidectm1Pli,Lepob/Lepob
Genetic Background: involves: STOCK Mlphln a Tgfawa1 Cdh23v Ednrbs

 MP:0001436 abnormal suckling behavior "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461]
Show

Allelic Composition: Cidectm1Pli/Cidectm1Pli,Lepob/Lepob
Genetic Background: involves: STOCK Mlphln a Tgfawa1 Cdh23v Ednrbs

 MP:0003638 abnormal response/metabolism to endogenous compounds "altered ability or inability to metabolize or respond to substances normally present in the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cidectm1Pli/Cidectm1Pli,Lepob/Lepob
Genetic Background: involves: STOCK Mlphln a Tgfawa1 Cdh23v Ednrbs

 MP:0004001 decreased hepatocyte proliferation "reduced growth and reproduction of hepatocyte cells of the liver" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Cidectm1Pli/Cidectm1Pli,Lepob/Lepob
Genetic Background: involves: STOCK Mlphln a Tgfawa1 Cdh23v Ednrbs

 MP:0005165 increased susceptibility to injury "greater than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cidectm1Pli/Cidectm1Pli,Lepob/Lepob
Genetic Background: involves: STOCK Mlphln a Tgfawa1 Cdh23v Ednrbs

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

 MP:0005517 decreased liver regeneration "less than the normal ability of liver to regenerate healthy tissue following partial hepatectomy" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cidectm1Pli/Cidectm1Pli,Lepob/Lepob
Genetic Background: involves: STOCK Mlphln a Tgfawa1 Cdh23v Ednrbs

 MP:0008412 increased cellular sensitivity to oxidative stress "greater incidence of cell death or enhanced production of reactive oxygen species after exposure to a variety of stress conditions including ionizing radiation, exposure to xenobiotics, inflammation, and phagocytosis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cidectm1Pli/Cidectm1Pli,Lepob/Lepob
Genetic Background: involves: STOCK Mlphln a Tgfawa1 Cdh23v Ednrbs

 MP:0009763 increased sensitivity to induced morbidity/mortality "decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cidectm1Pli/Cidectm1Pli,Lepob/Lepob
Genetic Background: involves: STOCK Mlphln a Tgfawa1 Cdh23v Ednrbs

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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