ENSMUSG00000023886


Mus musculus

Features
Gene ID: ENSMUSG00000023886
  
Biological name :Smoc2
  
Synonyms : Q8CD91 / Smoc2 / SPARC related modular calcium binding 2
  
Possible biological names infered from orthology : Q9H3U7
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A2
Gene start: 14279506
Gene end: 14404790
  
Corresponding Affymetrix probe sets: 10441902 (MoGene1.0st)   1415935_at (Mouse Genome 430 2.0 Array)   1431362_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000024660
NCBI entrez gene - 64074     See in Manteia.
MGI - MGI:1929881
RefSeq - NM_022315
RefSeq - XM_006524777
RefSeq Peptide - NP_071710
swissprot - Q8CD91
Ensembl - ENSMUSG00000023886
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SMOC2ENSG00000112562Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Smoc1 / SPARC related modular calcium binding 1 / Q9H4F8*ENSMUSG0000002113651


Protein motifs (from Interpro)
Interpro ID Name
 IPR000716  Thyroglobulin type-1
 IPR002048  EF-hand domain
 IPR002350  Kazal domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR019577  SPARC/Testican, calcium-binding domain
 IPR036857  Thyroglobulin type-1 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0010811 positive regulation of cell-substrate adhesion IDA
 biological_processGO:0030198 extracellular matrix organization IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005604 basement membrane IDA
 cellular_componentGO:0005614 interstitial matrix IDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005539 glycosaminoglycan binding IDA
 molecular_functionGO:0008201 heparin binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000441 wide skull 
Show

Allelic Composition: Gm36723em3Flv/Gm36723em3Flv
Genetic Background: C57BL/6-Gm36723em3Flv

 MP:0003760 short palate "abnormally decreased length to the roof of the oral cavity" [ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Gm36723em3Flv/Gm36723em3Flv
Genetic Background: C57BL/6-Gm36723em3Flv

 MP:0005166 decreased susceptiblity to injury "less than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gt(ROSA)26Sortm12.1Sia/Gt(ROSA)26Sor+,Haus6tm1.2Sdwb/Haus6tm1.2Sdwb
Genetic Background: B6.Cg-Haus6tm1.2Sdwb Gt(ROSA)26Sortm12.1Sia

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Scribtm1b(NCOM)Mfgc/Scribtm1b(NCOM)Mfgc
Genetic Background: C57BL/6N-Scribtm1a(NCOM)Mfgc/Tcp

 MP:0011862 decreased cranium length "having an decreased dorsal-to-ventral distance of the cranium" [MGI:mnk]
Show

Allelic Composition: Gm36723em3Flv/Gm36723em3Flv
Genetic Background: C57BL/6-Gm36723em3Flv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr