ENSMUSG00000024028


Mus musculus

Features
Gene ID: ENSMUSG00000024028
  
Biological name :Tff2
  
Synonyms : Tff2 / trefoil factor 2 (spasmolytic protein 1)
  
Possible biological names infered from orthology : Q03403 / trefoil factor 2
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A3.3
Gene start: 31141049
Gene end: 31144282
  
Corresponding Affymetrix probe sets: 10449661 (MoGene1.0st)   1422448_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000024826
NCBI entrez gene - 21785     See in Manteia.
MGI - MGI:1306805
RefSeq - NM_009363
RefSeq Peptide - NP_033389
swissprot - Q9QX97
Ensembl - ENSMUSG00000024028
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TFF2ENSGALG00000016165Gallus gallus
 TFF2ENSG00000160181Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tff1 / Q08423 / trefoil factor 1 / P04155*ENSMUSG0000002403229
Tff3 / Q62395 / Trefoil factor 3 ENSMUSG0000002402927


Protein motifs (from Interpro)
Interpro ID Name
 IPR000519  P-type trefoil domain
 IPR017957  P-type trefoil, conserved site
 IPR017994  P-type trefoil, chordata


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000470 abnormal stomach morphology "malformation of the sac-like structure of the digestive canal between the esophagus and the small intestine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Dmc1tm1Tkm/Dmc1tm1Tkm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000490 abnormal crypts of Lieberkuhn morphology "malformation or defects in the tubular intestinal glands found in the mucosal membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Dmc1tm1Tkm/Dmc1tm1Tkm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000503 excessive digestive secretion "increase in the production and/or release of a physiologically active substance (usually but not exclusively in liquid form) from a cell or a gland of the digestive system" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc]
Show

Allelic Composition: Dmc1tm1Tkm/Dmc1tm1Tkm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001663 abnormal digestive system physiology "altered function of the organ system that converts ingested food to nutrients and energy" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cntftm1Gdy/Cntftm1Gdy
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002419 abnormal innate immunity "anomaly in the function of the early phase of the response to infection; normally, it is present at all times, does not increase with exposure to specific pathogens, and does not discriminate between pathogens" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Cntftm1Gdy/Cntftm1Gdy
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002420 abnormal adaptive immunity "anomaly in the function of the response of antigen-specific lymphocytes to antigen, including the development of immunological memory" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Cntftm1Gdy/Cntftm1Gdy
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005165 increased susceptibility to injury "greater than the normal reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Dmc1tm1Tkm/Dmc1tm1Tkm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0010792 abnormal stomach mucosa morphology "any structural anomaly of the mucous layer of the stomach wall which contains the gastric pits and glands, and consists of epithelium, lamina propria, and the muscularis mucosae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dmc1tm1Tkm/Dmc1tm1Tkm
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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