ENSMUSG00000024213


Mus musculus

Features
Gene ID: ENSMUSG00000024213
  
Biological name :Nudt3
  
Synonyms : Diphosphoinositol polyphosphate phosphohydrolase 1 / Nudt3 / Q9JI46
  
Possible biological names infered from orthology : nudix hydrolase 3 / O95989
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A3.3
Gene start: 27579382
Gene end: 27623465
  
Corresponding Affymetrix probe sets: 10449363 (MoGene1.0st)   1451575_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135890
Ensembl peptide - ENSMUSP00000110536
Ensembl peptide - ENSMUSP00000059061
Ensembl peptide - ENSMUSP00000025050
Ensembl peptide - ENSMUSP00000135175
NCBI entrez gene - 56409     See in Manteia.
MGI - MGI:1928484
RefSeq - NM_019837
RefSeq - NM_001291046
RefSeq Peptide - NP_062811
RefSeq Peptide - NP_001277975
swissprot - Q9JI46
swissprot - B2KF67
swissprot - H3BJY4
swissprot - H3BLR8
swissprot - I1E4X7
Ensembl - ENSMUSG00000024213
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nudt3aENSDARG00000016256Danio rerio
 nudt3bENSDARG00000042123Danio rerio
 NUDT3ENSGALG00000002830Gallus gallus
 NUDT3ENSG00000272325Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nudt4 / Q8R2U6 / Mus musculus nudix (nucleoside diphosphate linked moiety X)-type motif 4 (Nudt4), transcript variant 1, mRNA. / NUDT4B* / Q9NZJ9* / nudix hydrolase 4* / nudix hydrolase 4B*ENSMUSG0000002002977
P0C027 / P0C028 / Nudt10 / Diphosphoinositol polyphosphate phosphohydrolase 3-alpha / Q96G61* / NUDT11* / Q8NFP7* / nudix hydrolase 10* / nudix hydrolase 11*ENSMUSG0000007329374
Nudt11 / P0C028 / P0C027 / Diphosphoinositol polyphosphate phosphohydrolase 3-alpha / NUDT10* / Q8NFP7* / Q96G61* / nudix hydrolase 11* / nudix hydrolase 10*ENSMUSG0000007329574


Protein motifs (from Interpro)
Interpro ID Name
 IPR000086  NUDIX hydrolase domain
 IPR015797  NUDIX hydrolase-like domain superfamily
 IPR020084  NUDIX hydrolase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0071543 diphosphoinositol polyphosphate metabolic process IBA
 biological_processGO:0071544 diphosphoinositol polyphosphate catabolic process IEA
 biological_processGO:1901907 diadenosine pentaphosphate catabolic process IBA
 biological_processGO:1901909 diadenosine hexaphosphate catabolic process IBA
 biological_processGO:1901911 adenosine 5"-(hexahydrogen pentaphosphate) catabolic process IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0000298 endopolyphosphatase activity IBA
 molecular_functionGO:0008486 diphosphoinositol-polyphosphate diphosphatase activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0034431 bis(5"-adenosyl)-hexaphosphatase activity IBA
 molecular_functionGO:0034432 bis(5"-adenosyl)-pentaphosphatase activity IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050072 m7G(5")pppN diphosphatase activity IBA
 molecular_functionGO:0052840 inositol diphosphate tetrakisphosphate diphosphatase activity IEA
 molecular_functionGO:0052841 inositol bisdiphosphate tetrakisphosphate diphosphatase activity IEA
 molecular_functionGO:0052842 inositol diphosphate pentakisphosphate diphosphatase activity IEA
 molecular_functionGO:0052843 inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity IEA
 molecular_functionGO:0052844 inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity IEA
 molecular_functionGO:0052845 inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity IEA
 molecular_functionGO:0052846 inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity IEA
 molecular_functionGO:0052847 inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity IEA
 molecular_functionGO:0052848 inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of pyrophosphates in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr