ENSMUSG00000024583


Mus musculus
activityTxnl1domainsuperfamilydisulfideoxidoreductasepiththioredoxincellularreductasegalactose-binding-likeconservedsitethioredoxin-likeresponseoxidativestresscellredoxhomeostasisoxidation-reductionprocessoxidantdetoxificationproteasomecomplexnucleuscytoplasmcytosolthioredoxin-disulfideprotein

Features
Gene ID: ENSMUSG00000024583
  
Biological name :Txnl1
  
Synonyms : Q8CDN6 / thioredoxin-like 1 / Txnl1
  
Possible biological names infered from orthology : O43396
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: E1
Gene start: 63662801
Gene end: 63692359
  
Corresponding Affymetrix probe sets: 10459375 (MoGene1.0st)   1423299_at (Mouse Genome 430 2.0 Array)   1435235_at (Mouse Genome 430 2.0 Array)   1436947_a_at (Mouse Genome 430 2.0 Array)   1437905_at (Mouse Genome 430 2.0 Array)   1437906_x_at (Mouse Genome 430 2.0 Array)   1455866_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025476
NCBI entrez gene - 53382     See in Manteia.
MGI - MGI:1860078
RefSeq - NM_016792
RefSeq Peptide - NP_058072
swissprot - Q8CDN6
Ensembl - ENSMUSG00000024583
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 txnl1ENSDARG00000011921Danio rerio
 TXNL1ENSGALG00000033862Gallus gallus
 TXNL1ENSG00000091164Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Txn1 / P10639 / thioredoxin 1 / TXN* / P10599* / thioredoxin*ENSMUSG0000002836715
Q69AB2 / Txndc8 / thioredoxin domain containing 8 / Q6A555*ENSMUSG0000003870914
Txndc2 / thioredoxin domain containing 2 (spermatozoa) / Q86VQ3* / thioredoxin domain containing 2*ENSMUSG0000005061212


Protein motifs (from Interpro)
Interpro ID Name
 IPR008979  Galactose-binding-like domain superfamily
 IPR010400  PITH domain
 IPR013766  Thioredoxin domain
 IPR017937  Thioredoxin, conserved site
 IPR036249  Thioredoxin-like superfamily
 IPR037047  PITH domain superfamily


Gene Ontology (GO)
response to stressresponse to chemicalcellular response to stimulusregulation of biological qualityoxidation-reduction processresponse to stressresponse to chemicalcellular response to stimulusregulation of biological qualityoxidation-reduction processresponse to stressresponse to chemicalcellular response to stimulusregulation of biological qualityoxidation-reduction processresponse to stressresponse to chemicalcellular response to stimulusregulation of biological qualityoxidation-reduction processresponse to stressresponse to chemicalcellular response to stimulusregulation of biological qualityoxidation-reduction processresponse to stressresponse to chemicalcellular response to stimulusregulation of biological qualityoxidation-reduction processresponse to stressresponse to chemicalcellular response to stimulusregulation of biological qualityoxidation-reduction processresponse to stressresponse to chemicalcellular response to stimulusregulation of biological qualityoxidation-reduction processresponse to stressresponse to chemicalcellular response to stimulusregulation of biological qualityoxidation-reduction processresponse to stressresponse to chemicalcellular response to stimulusregulation of biological qualityoxidation-reduction processresponse to stressresponse to stressresponse to chemicalresponse to chemicalcellular response to stimulucellular response to stimulusregulation of biological quaregulation of biological qualityoxidation-reduction processoxidation-reduction process
oxidoreductase activityoxidoreductase activityoxidoreductase activityoxidoreductase activityoxidoreductase activityoxidoreductase activityoxidoreductase activityoxidoreductase activityoxidoreductase activityoxidoreductase activityoxidoreductase activityoxidoreductase activity
cellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellcellprotein-containing complexprotein-containing complexorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0034599 cellular response to oxidative stress IBA
 biological_processGO:0045454 cell redox homeostasis IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0000502 proteasome complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004791 thioredoxin-disulfide reductase activity IBA
 molecular_functionGO:0015035 protein disulfide oxidoreductase activity IBA
 molecular_functionGO:0015036 disulfide oxidoreductase activity IEA
 molecular_functionGO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IBA
 molecular_functionGO:0047134 protein-disulfide reductase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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