ENSMUSG00000024608


Mus musculus

Features
Gene ID: ENSMUSG00000024608
  
Biological name :Rps14
  
Synonyms : 40S ribosomal protein S14 / P62264 / Rps14
  
Possible biological names infered from orthology : P62263 / ribosomal protein S14
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: E1
Gene start: 60774510
Gene end: 60778546
  
Corresponding Affymetrix probe sets: 10456001 (MoGene1.0st)   10498155 (MoGene1.0st)   1436586_x_at (Mouse Genome 430 2.0 Array)   1437706_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113504
Ensembl peptide - ENSMUSP00000122985
Ensembl peptide - ENSMUSP00000114478
Ensembl peptide - ENSMUSP00000025511
Ensembl peptide - ENSMUSP00000113081
NCBI entrez gene - 20044     See in Manteia.
MGI - MGI:98107
RefSeq - NM_020600
RefSeq Peptide - NP_065625
swissprot - D3Z7I1
swissprot - D3YVF4
swissprot - P62264
Ensembl - ENSMUSG00000024608
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rps14ENSDARG00000036629Danio rerio
 RPS14ENSGALG00000004588Gallus gallus
 RPS14ENSG00000164587Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001971  Ribosomal protein S11
 IPR018102  Ribosomal S11, conserved site
 IPR036967  Ribosomal protein S11 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000028 ribosomal small subunit assembly ISO
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0006412 translation ISO
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0030218 erythrocyte differentiation ISO
 biological_processGO:0030490 maturation of SSU-rRNA ISS
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0022627 cytosolic small ribosomal subunit ISO
 cellular_componentGO:0031012 extracellular matrix ISO
 molecular_functionGO:0003723 RNA binding ISS
 molecular_functionGO:0003735 structural constituent of ribosome IBA
 molecular_functionGO:0045182 translation regulator activity ISO
 molecular_functionGO:0048027 mRNA 5"-UTR binding IBA
 molecular_functionGO:0070181 small ribosomal subunit rRNA binding IBA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000691 enlarged spleen "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0001606 impaired hematopoiesis "atypical process of blood cell formation with the result of fewer of these cells being formed" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0002397 abnormal bone marrow morphology "structural anomalies in the soft tissue that fills the cavities of bones" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0002417 abnormal megakaryocyte morphology/development "anomalous structure or formation of the very large cells found in the bone marrow that release platelets" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0003077 abnormal cell cycle "failure to progress or abnormal progression through the stages of of the cell cycle" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91266]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0003155 abnormal telomere length "abnormal length of the terminal section of a chromosome which has a specialized structure and which is involved in chromosomal replication and stability; normal length is a few hundred base pairs" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0003405 abnormal platelet shape 
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0005505 increased platelet count "greater than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0006042 increased apoptosis "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0008801 abnormal erythroid progenitor cell morphology "any structural anomaly of a progenitor cell committed to the erythroid lineage" [CL:0000038]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0009278 abnormal bone marrow cell physiology "any functional anomaly of any of the cells found in the blood" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

 MP:0013272 abnormal translation "any anomaly in the cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain; translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA; translation ends with the release of a polypeptide chain from the ribosome" [GO:0006412]
Show

Allelic Composition: Saa3tm1(KOMP)Vlcg/Saa3+
Genetic Background: involves: C57BL/6NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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