ENSMUSG00000024673


Mus musculus

Features
Gene ID: ENSMUSG00000024673
  
Biological name :Ms4a1
  
Synonyms : membrane-spanning 4-domains, subfamily A, member 1 / Ms4a1 / P19437
  
Possible biological names infered from orthology : membrane spanning 4-domains A1 / P11836
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: A
Gene start: 11249675
Gene end: 11266241
  
Corresponding Affymetrix probe sets: 10466172 (MoGene1.0st)   1423226_at (Mouse Genome 430 2.0 Array)   1450912_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000126422
NCBI entrez gene - 12482     See in Manteia.
MGI - MGI:88321
RefSeq - NM_007641
RefSeq Peptide - NP_031667
swissprot - P19437
swissprot - Q542S5
Ensembl - ENSMUSG00000024673
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MS4A1ENSG00000156738Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007237  CD20-like family
 IPR030417  Membrane-spanning 4-domains subfamily A
 IPR030418  B-lymphocyte antigen CD20


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042113 B cell activation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002458 abnormal B cell number "deviation from the normal number of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: H2afxtm1Nus/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002459 abnormal B cell physiology "abnormal function of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: H2afxtm1Nus/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0004978 decreased B-1 B cell number "reduced number of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: H2afxtm1Nus/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0008189 increased transitional stage B cell number "greater number of immature B cells of an intermediate stage between the pre-B cell stage and the mature naive stage; transitional B cells express surface immunoglobulin, and are subject to the process of B cell selection" [CL:0000818, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: H2afxtm1Nus/H2afx+,Trp53tm1Brd/Trp53tm1Brd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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