ENSMUSG00000024737


Mus musculus

Features
Gene ID: ENSMUSG00000024737
  
Biological name :Slc15a3
  
Synonyms : Q8BPX9 / Slc15a3 / Solute carrier family 15 member 3
  
Possible biological names infered from orthology : Q8IY34
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 10839727
Gene end: 10859362
  
Corresponding Affymetrix probe sets: 10461558 (MoGene1.0st)   1420697_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025646
NCBI entrez gene - 65221     See in Manteia.
MGI - MGI:1929691
RefSeq - NM_023044
RefSeq Peptide - NP_075531
swissprot - Q8BPX9
Ensembl - ENSMUSG00000024737
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8IY34ENSG00000110446Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q91W98 / Slc15a4 / Solute carrier family 15 member 4 / Q8N697*ENSMUSG0000002941648
Slc15a2 / solute carrier family 15 (H+/peptide transporter), member 2 / Q16348* / solute carrier family 15 member 2*ENSMUSG0000002289921
Q9JIP7 / Slc15a1 / solute carrier family 15 (oligopeptide transporter), member 1 / P46059* / solute carrier family 15 member 1*ENSMUSG0000002555721
Q8CBB2 / Slc15a5 / Solute carrier family 15 member 5 / A6NIM6*ENSMUSG0000004437819


Protein motifs (from Interpro)
Interpro ID Name
 IPR000109  Proton-dependent oligopeptide transporter family
 IPR018456  PTR2 family proton/oligopeptide symporter, conserved site
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006857 oligopeptide transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0015833 peptide transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0015293 symporter activity IEA
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Proton/oligopeptide cotransporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002591 decreased mean corpuscular volume "less than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Skida1tm1.1(KOMP)Wtsi/Skida1tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Skida1tm1.1(KOMP)Wtsi/Ucd

 MP:0002965 hyperalbuminemia "blood albumin concentration above the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
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Allelic Composition: Skida1tm1.1(KOMP)Wtsi/Skida1tm1.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Skida1tm1.1(KOMP)Wtsi/Ucd

 MP:0006173 abnormal Langerhans cell morphology/development "anomaly in the formation or structure of phagocytic dendritic cells principally found in the epidemis and mucosal epithelium" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95147]
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Allelic Composition: Osr2tm2(cre)Jian/Osr2+,Tg(CAG-Bmp4,-EGFP)1Ypc/0
Genetic Background: involves: 129S1/Sv * C57BL/6J * CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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