ENSMUSG00000025078


Mus musculus
thioredoxin-likecellNhlrc2nhlrepeatsix-bladedbeta-propellertolb-likefoldthioredoxindomainsuperfamilybiologicalprocessredoxhomeostasiscellularcomponentmolecularfunctionproteinbindingplateletdegranulationpreweaninglethality

Features
Gene ID: ENSMUSG00000025078
  
Biological name :Nhlrc2
  
Synonyms : Nhlrc2 / NHL repeat-containing protein 2 / Q8BZW8
  
Possible biological names infered from orthology : NHL repeat containing 2 / Q8NBF2
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: D2
Gene start: 56548261
Gene end: 56598846
  
Corresponding Affymetrix probe sets: 10464153 (MoGene1.0st)   1429145_at (Mouse Genome 430 2.0 Array)   1433929_at (Mouse Genome 430 2.0 Array)   1453048_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000071370
NCBI entrez gene - 66866     See in Manteia.
MGI - MGI:1914116
RefSeq - XM_006527267
RefSeq - NM_025811
RefSeq Peptide - NP_080087
swissprot - Q8BZW8
swissprot - B2RR26
Ensembl - ENSMUSG00000025078
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nhlrc2ENSDARG00000089581Danio rerio
 NHLRC2ENSGALG00000008946Gallus gallus
 NHLRC2ENSG00000196865Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001258  NHL repeat
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR012336  Thioredoxin-like fold
 IPR013766  Thioredoxin domain
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
regulation of biological qualityregulation of biological qualityregulation of biological qualityregulation of biological qualityregulation of biological qualityregulation of biological qualityregulation of biological qualityregulation of biological qualityregulation of biological qualityregulation of biological qualityregulation of biological qualityregulation of biological quality
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellcellcellcellcellcellcellcellcellcellcellcell
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0045454 cell redox homeostasis IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
mortality/agingmortality/agingmortality/agingmortality/agingmortality/agingmortality/agingmortality/agingmortality/agingmortality/agingmortality/agingmortality/agingmortality/aging
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Nek7tm1b(EUCOMM)Hmgu/Nek7tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nek7tm1b(EUCOMM)Hmgu/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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