ENSMUSG00000025163


Mus musculus

Features
Gene ID: ENSMUSG00000025163
  
Biological name :Cd7
  
Synonyms : Cd7 / P50283 / T-cell antigen CD7
  
Possible biological names infered from orthology : CD7 molecule / P09564
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E2
Gene start: 121036747
Gene end: 121039418
  
Corresponding Affymetrix probe sets: 10394054 (MoGene1.0st)   1419711_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026159
NCBI entrez gene - 12516     See in Manteia.
MGI - MGI:88344
RefSeq - NM_009854
RefSeq Peptide - NP_033984
swissprot - P50283
swissprot - Q3U4A8
Ensembl - ENSMUSG00000025163
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CD7ENSG00000173762Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0048873 homeostasis of number of cells within a tissue IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000714 increased thymocyte number "greater than expected number of precursors to T cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa

Allelic Composition: Cd7tm1Bfh/Cd7tm1Bfh
Genetic Background: B6.129-Cd7tm1Bfh

 MP:0005079 defective cytotoxic T cell cytolysis "impaired ability of these cells to destroy or dissolve targeted cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:6692]
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Allelic Composition: Cd7tm1Bfh/Cd7tm1Bfh
Genetic Background: B6.129-Cd7tm1Bfh

 MP:0005091 increased double-positive T cell count "greater than the expected number of the subset of T cells found in the thymus that express both CD4 and CD8" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa

Allelic Composition: Cd7tm1Bfh/Cd7tm1Bfh
Genetic Background: B6.129-Cd7tm1Bfh

 MP:0008567 decreased interferon-gamma secretion "reduction in the production or release of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation" [MESH:D12.644.276.374.440.893]
Show

Allelic Composition: Cd7tm1Bfh/Cd7tm1Bfh
Genetic Background: B6.129-Cd7tm1Bfh

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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