ENSMUSG00000025333


Mus musculus

Features
Gene ID: ENSMUSG00000025333
  
Biological name :Gpr143
  
Synonyms : Gpr143 / G protein-coupled receptor 143 / P70259
  
Possible biological names infered from orthology : P51810
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: F3
Gene start: 152781921
Gene end: 152808646
  
Corresponding Affymetrix probe sets: 10602677 (MoGene1.0st)   1420581_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026383
NCBI entrez gene - 18241     See in Manteia.
MGI - MGI:107193
RefSeq - XM_006528746
RefSeq - NM_010951
RefSeq Peptide - NP_035081
swissprot - P70259
swissprot - Q549B6
Ensembl - ENSMUSG00000025333
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpr143ENSDARG00000034572Danio rerio
 GPR143ENSGALG00000016615Gallus gallus
 GPR143ENSG00000101850Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001414  G-protein coupled receptor 143


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0032400 melanosome localization IEA
 biological_processGO:0032402 melanosome transport IEA
 biological_processGO:0032438 melanosome organization IEA
 biological_processGO:0035584 calcium-mediated signaling using intracellular calcium source IEA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling IEA
 biological_processGO:0050848 regulation of calcium-mediated signaling IEA
 biological_processGO:1902908 regulation of melanosome transport IMP
 biological_processGO:1903056 regulation of melanosome organization IMP
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane ISO
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0033162 melanosome membrane ISO
 cellular_componentGO:0042470 melanosome IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity ISO
 molecular_functionGO:0035240 dopamine binding ISO
 molecular_functionGO:0035643 L-DOPA receptor activity IEA
 molecular_functionGO:0072544 L-DOPA binding ISO
 molecular_functionGO:0072545 tyrosine binding ISO


Pathways (from Reactome)
Pathway description
Amine ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001332 abnormal optic nerve innervation "misprojection or aberrant target finding of the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Bmp5se-Ca/Bmp5+
Genetic Background: SEACGn.CB-Bmp5se-Ca

 MP:0002864 abnormal ocular fundus morphology "malformation of the posterior concave interior of the eye, consisting of the retina, the choroid, the posterior segment of the sclera, the optic disk, and blood vessels, visible by an ophthalmoscope" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Bmp5se-Ca/Bmp5+
Genetic Background: SEACGn.CB-Bmp5se-Ca

 MP:0005075 abnormal melanosome morphology "anomalous structure of these tissue-specific cytoplasmic organelles within which melanin pigments are synthesized and stored" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346]
Show

Allelic Composition: Bmp5se-Ca/Bmp5+
Genetic Background: SEACGn.CB-Bmp5se-Ca

 MP:0005101 abnormal ciliary body pigmentation "anomalous coloring of the thickened portion of the vascular tunic, which lies between the choroid and the iris" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Bmp5se-Ca/Bmp5+
Genetic Background: SEACGn.CB-Bmp5se-Ca

 MP:0005103 abnormal retinal pigmentation "anomalous coloring of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Bmp5se-Ca/Bmp5+
Genetic Background: SEACGn.CB-Bmp5se-Ca

 MP:0005199 abnormal iris pigment epithelium "anomaly in the epithelial layer of the iris composed of cells containing pigment granules " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Bmp5se-Ca/Bmp5+
Genetic Background: SEACGn.CB-Bmp5se-Ca

 MP:0005201 abnormal retinal pigment epithelium morphology "anomaly in the epithelial layer of the retina composed of cells containing pigment granules " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Bmp5se-Ca/Bmp5+
Genetic Background: SEACGn.CB-Bmp5se-Ca

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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