ENSMUSG00000025738


Mus musculus

Features
Gene ID: ENSMUSG00000025738
  
Biological name :Fbxl16
  
Synonyms : A2RT62 / F-box/LRR-repeat protein 16 / Fbxl16
  
Possible biological names infered from orthology : F-box and leucine rich repeat protein 16 / Q8N461
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A3.3
Gene start: 25809085
Gene end: 25821244
  
Corresponding Affymetrix probe sets: 10442887 (MoGene1.0st)   1440286_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000048562
NCBI entrez gene - 214931     See in Manteia.
MGI - MGI:2448488
RefSeq - NM_001164225
RefSeq - XM_006524020
RefSeq Peptide - NP_001157697
swissprot - B2RPY3
swissprot - A2RT62
Ensembl - ENSMUSG00000025738
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxl16ENSDARG00000060915Danio rerio
 FBXL16ENSGALG00000002443Gallus gallus
 FBXL16ENSG00000127585Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fbxl2 / Q8BH16 / F-box/LRR-repeat protein 2 / Q9UKC9* / F-box and leucine rich repeat protein 2*ENSMUSG0000003250720
Fbxl20 / Q9CZV8 / F-box/LRR-repeat protein 20 / Q96IG2* / F-box and leucine rich repeat protein 20*ENSMUSG0000002088319
Fbxl7 / Q5BJ29 / F-box/LRR-repeat protein 7 / Q9UJT9* / F-box and leucine rich repeat protein 7*ENSMUSG0000004355619
Fbxl4 / Q8BH70 / F-box/LRR-repeat protein 4 / Q9UKA2* / F-box and leucine rich repeat protein 4*ENSMUSG0000004041018
Fbxl13 / Q8CDU4 / F-box/LRR-repeat protein 13 / Q8NEE6* / F-box and leucine rich repeat protein 13*ENSMUSG0000004852018
Fbxl17 / Q9QZN1 / F-box/LRR-repeat protein 17 / Q9UF56* / F-box and leucine rich repeat protein 17*ENSMUSG0000002396517
Fbxl14 / Q8BID8 / F-box/LRR-repeat protein 14 / Q8N1E6* / F-box and leucine rich repeat protein 14*ENSMUSG0000003001917
Fbxl15 / Q91W61 / F-box/LRR-repeat protein 15 / Q9H469* / F-box and leucine rich repeat protein 15*ENSMUSG0000002522612
Lrrc29 / leucine rich repeat containing 29 / Q8WV35*ENSMUSG000000416799


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR006553  Leucine-rich repeat, cysteine-containing subtype
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISO
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002080 prenatal lethality "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

 MP:0002626 increased heart rate "greater than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

 MP:0003050 abnormal sacral vertebrae morphology "malformation of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

 MP:0005333 decreased heart rate "fewer than average resting heart beats per minute" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:84764]
Show

Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

 MP:0011959 abnormal eye posterior chamber depth "anomaly in the distance between the iris and the lens at the center plane (maximum distance) of the posterior chamber, compared to controls" [MGI:csmith]
Show

Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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