ENSMUSG00000025774


Mus musculus

Features
Gene ID: ENSMUSG00000025774
  
Biological name :Crisp4
  
Synonyms : Crisp4 / cysteine-rich secretory protein 4
  
Possible biological names infered from orthology : CRISP1 / cysteine rich secretory protein 1 / P54107
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: A3
Gene start: 18115191
Gene end: 18145902
  
Corresponding Affymetrix probe sets: 10353320 (MoGene1.0st)   1431468_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026876
Ensembl peptide - ENSMUSP00000110997
Ensembl peptide - ENSMUSP00000111001
NCBI entrez gene - 78081     See in Manteia.
MGI - MGI:1925331
RefSeq - XM_006495591
RefSeq - NM_001347048
RefSeq - NM_030033
RefSeq - XM_006495588
RefSeq - XM_006495589
RefSeq - XM_006495590
RefSeq Peptide - NP_084309
RefSeq Peptide - NP_001333976
RefSeq Peptide - NP_001333977
swissprot - G5E862
swissprot - Q9D259
swissprot - E9PVG4
Ensembl - ENSMUSG00000025774
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01068499.1ENSDARG00000103034Danio rerio
 CRISP1ENSG00000124812Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q03401 / Crisp1 / Cysteine-rich secretory protein 1 / CRISP3* / P54108* / cysteine rich secretory protein 3*ENSMUSG0000002543135
Crisp2 / P16563 / Cysteine-rich secretory protein 2 / P16562*ENSMUSG0000002393032
Crisp3 / Q03402 / Cysteine-rich secretory protein 3 / P54108*ENSMUSG0000002543330
Q8BZQ2 / Crispld2 / Cysteine-rich secretory protein LCCL domain-containing 2 / Q9H0B8*ENSMUSG0000003182524
Pi16 / peptidase inhibitor 16 / Q6UXB8*ENSMUSG0000002401122
Q8CGD2 / Crispld1 / Cysteine-rich secretory protein LCCL domain-containing 1 / Q9H336*ENSMUSG0000002577622
Glipr1 / Q9CWG1 / Glioma pathosis-related protein 1 / P48060* / GLI pathogenesis related 1*ENSMUSG0000005688822
Q9DAG6 / Glipr1l1 / GLIPR1-like protein 1 / Q6UWM5* / GLIPR1 like 1*ENSMUSG0000002021321
Q9CQ35 / Glipr1l2 / GLIPR1-like protein 2 / Q4G1C9* / GLIPR1 like 2*ENSMUSG0000002021421
Pi15 / peptidase inhibitor 15 / O43692*ENSMUSG0000006778019
Glipr1l3 / Q6UWM5* / GLIPR1L1* / GLIPR1 like 1*ENSMUSG0000011261119
A2A5I3 / R3hdml / R3H domain containing-like / Q9H3Y0*ENSMUSG0000007894917


Protein motifs (from Interpro)
Interpro ID Name
 IPR001283  Cysteine-rich secretory protein, allergen V5/Tpx-1-related
 IPR003582  ShKT domain
 IPR013871  Cysteine-rich secretory protein
 IPR014044  CAP domain
 IPR018244  Allergen V5/Tpx-1-related, conserved site
 IPR035940  CAP superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007339 binding of sperm to zona pellucida IMP
 biological_processGO:0060046 regulation of acrosome reaction IMP
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005246 calcium channel regulator activity IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004542 impaired acrosome reaction "abnormality in the cellular exocytosis that allows sperm to penetrate the zona pellucida of ovulated eggs" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Esr1tm1.1Ohl/Esr1tm1.1Ohl
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lama5tm2Jhm/Lama5tm1Jhm,Tg(NPHS2-cre)295Lbh/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr