ENSMUSG00000026063


Mus musculus

Features
Gene ID: ENSMUSG00000026063
  
Biological name :Pih1d3
  
Synonyms : Pih1d3 / Protein PIH1D3 / Q3KNI6
  
Possible biological names infered from orthology : PIH1 domain containing 3 / Q9NQM4
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: B
Gene start: 31222838
Gene end: 31224288
  
Corresponding Affymetrix probe sets: 10345197 (MoGene1.0st)   1430400_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000127665
NCBI entrez gene - 74708     See in Manteia.
MGI - MGI:1921958
RefSeq - NM_029062
RefSeq Peptide - NP_083338
swissprot - Q3KNI6
Ensembl - ENSMUSG00000026063
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pih1d3ENSDARG00000038612Danio rerio
 PIH1D3ENSGALG00000004870Gallus gallus
 PIH1D3ENSG00000080572Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pih1h3b / PIH1D3* / Q9NQM4* / PIH1 domain containing 3*ENSMUSG0000004243391


Protein motifs (from Interpro)
Interpro ID Name
 IPR008978  HSP20-like chaperone
 IPR012981  PIH1 domain
 IPR026697  PIH1 domain-containing protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003341 cilium movement ISS
 biological_processGO:0030317 flagellated sperm motility ISS
 biological_processGO:0070286 axonemal dynein complex assembly IMP
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0051087 chaperone binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic Background: B6.129P2(FVB)-Abcc2tm1Ahs

 MP:0002160 abnormal reproductive system morphology "structural or developmental anomaly of any of the tissues involved in the reproductive system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic Background: B6.129P2(FVB)-Abcc2tm1Ahs

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic Background: B6.129P2(FVB)-Abcc2tm1Ahs

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic Background: B6.129P2(FVB)-Abcc2tm1Ahs

 MP:0003698 abnormal male reproductive system physiology "anomaly in the function of the male organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic Background: B6.129P2(FVB)-Abcc2tm1Ahs

 MP:0008892 abnormal sperm flagellum "any strucutral anomaly of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MESH:A05.360.490.890.840]
Show

Allelic Composition: Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic Background: B6.129P2(FVB)-Abcc2tm1Ahs

 MP:0009239 short sperm flagellum "decreased length of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic Background: B6.129P2(FVB)-Abcc2tm1Ahs

 MP:0009242 thin sperm flagellum "reduced thickness of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic Background: B6.129P2(FVB)-Abcc2tm1Ahs

 MP:0009838 abnormal sperm axoneme morphology "any structural abnormality of the central core of the sperm flagellum, composed of a ring of 9 outer microtubule doublets surrounding a central pair; inner and outer dynein arms project from each of the outer 9 doublets, and these arms are responsible for generating the motive force of the flagellum; in addition, 9 radial spokes, each of which originates from 1 of the 9 outer microtubular doublet pairs, project inward toward the central pair in a helical fashion" [PMID:14581499]
Show

Allelic Composition: Abcc2tm1Ahs/Abcc2tm1Ahs
Genetic Background: B6.129P2(FVB)-Abcc2tm1Ahs

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr