ENSMUSG00000026150


Mus musculus

Features
Gene ID: ENSMUSG00000026150
  
Biological name :Mff
  
Synonyms : Mff / Mitochondrial fission factor / Q6PCP5
  
Possible biological names infered from orthology : Q9GZY8
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: C5
Gene start: 82724890
Gene end: 82752394
  
Corresponding Affymetrix probe sets: 10347862 (MoGene1.0st)   1451572_a_at (Mouse Genome 430 2.0 Array)   1456582_x_at (Mouse Genome 430 2.0 Array)   1456736_x_at (Mouse Genome 430 2.0 Array)   1457371_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125230
Ensembl peptide - ENSMUSP00000125223
Ensembl peptide - ENSMUSP00000125629
Ensembl peptide - ENSMUSP00000072784
Ensembl peptide - ENSMUSP00000077446
Ensembl peptide - ENSMUSP00000123713
Ensembl peptide - ENSMUSP00000124164
Ensembl peptide - ENSMUSP00000124200
Ensembl peptide - ENSMUSP00000124334
Ensembl peptide - ENSMUSP00000125005
NCBI entrez gene - 75734     See in Manteia.
MGI - MGI:1922984
RefSeq - XM_017312652
RefSeq - XM_006496562
RefSeq - XM_006496563
RefSeq - XM_006496564
RefSeq - XM_006496565
RefSeq - XM_006496566
RefSeq - XM_006496567
RefSeq - XM_006496568
RefSeq - XM_006496569
RefSeq - XM_006496572
RefSeq - XM_017312643
RefSeq - XM_017312646
RefSeq - NM_001310695
RefSeq - NM_001310697
RefSeq - NM_001310699
RefSeq - NM_029409
RefSeq - XM_006496556
RefSeq - XM_006496557
RefSeq - XM_006496558
RefSeq - XM_006496559
RefSeq - XM_006496560
RefSeq Peptide - NP_001297626
RefSeq Peptide - NP_001297628
RefSeq Peptide - NP_083685
RefSeq Peptide - NP_001297624
swissprot - E0CYI3
swissprot - E0CYB9
swissprot - F6VAL0
swissprot - Q6PCP5
swissprot - F7B1A4
swissprot - F7BC60
swissprot - F7CTF8
Ensembl - ENSMUSG00000026150
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mffENSDARG00000053753Danio rerio
 zgc:110130ENSDARG00000039203Danio rerio
 MFFENSGALG00000003079Gallus gallus
 MFFENSG00000168958Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008518  FATE/Miff/Tango-11


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000266 mitochondrial fission IMP
 biological_processGO:0001836 release of cytochrome c from mitochondria IEA
 biological_processGO:0006626 protein targeting to mitochondrion IEA
 biological_processGO:0008053 mitochondrial fusion ISS
 biological_processGO:0010821 regulation of mitochondrion organization IEA
 biological_processGO:0016559 peroxisome fission IEA
 biological_processGO:0043653 mitochondrial fragmentation involved in apoptotic process IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0070584 mitochondrion morphogenesis ISO
 biological_processGO:0090141 positive regulation of mitochondrial fission ISS
 biological_processGO:0090200 positive regulation of release of cytochrome c from mitochondria IEA
 biological_processGO:0090314 positive regulation of protein targeting to membrane ISS
 biological_processGO:1900063 regulation of peroxisome organization IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IDA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0032592 integral component of mitochondrial membrane IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001657 abnormal induced morbidity/mortality "differences from the expected diseased state or death caused by an external intervention" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Olfr151tm42(Mc4r)Mom/Olfr151tm42(Mc4r)Mom
Genetic Background: B6;129P2-Olfr151tm42(Mc4r)Mom/MomJ

 MP:0003038 decreased infarction size "decreased size of necrotic area from normal of the myocardium resulting from a sudden insufficiency of arterial or venous blood supply due to emboli, thrombi or mechanical factors" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Olfr151tm42(Mc4r)Mom/Olfr151tm42(Mc4r)Mom
Genetic Background: B6;129P2-Olfr151tm42(Mc4r)Mom/MomJ

 MP:0006043 decreased apoptosis "less than normal cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Olfr151tm42(Mc4r)Mom/Olfr151tm42(Mc4r)Mom
Genetic Background: B6;129P2-Olfr151tm42(Mc4r)Mom/MomJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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