ENSMUSG00000026307


Mus musculus

Features
Gene ID: ENSMUSG00000026307
  
Biological name :Scly
  
Synonyms : Scly / selenocysteine lyase
  
Possible biological names infered from orthology : Q96I15
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: D
Gene start: 91298338
Gene end: 91321075
  
Corresponding Affymetrix probe sets: 10348558 (MoGene1.0st)   1417671_at (Mouse Genome 430 2.0 Array)   1441192_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119979
Ensembl peptide - ENSMUSP00000116824
Ensembl peptide - ENSMUSP00000122449
Ensembl peptide - ENSMUSP00000137796
Ensembl peptide - ENSMUSP00000027532
Ensembl peptide - ENSMUSP00000114759
Ensembl peptide - ENSMUSP00000116382
NCBI entrez gene - 50880     See in Manteia.
MGI - MGI:1355310
RefSeq - XM_006529746
RefSeq - NM_016717
RefSeq - XM_006529743
RefSeq - XM_006529744
RefSeq - XM_006529745
RefSeq Peptide - NP_057926
swissprot - D3Z3I6
swissprot - A0A0R4J069
swissprot - D3Z7G6
swissprot - F6ZFP8
swissprot - F7BB44
swissprot - M0QWF1
swissprot - F7D651
Ensembl - ENSMUSG00000026307
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sclyENSDARG00000073813Danio rerio
 SCLYENSGALG00000030194Gallus gallus
 SCLYENSG00000132330Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nfs1 / Q9Z1J3 / Cysteine desulfurase, mitochondrial / Q9Y697* / AL109827.1* / NFS1, cysteine desulfurase*ENSMUSG0000002761830


Protein motifs (from Interpro)
Interpro ID Name
 IPR000192  Aminotransferase class V domain
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR016454  Cysteine desulfurase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016261 selenocysteine catabolic process IEA
 cellular_componentGO:1902494 catalytic complex IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0009000 selenocysteine lyase activity IEA
 molecular_functionGO:0016597 amino acid binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0070279 vitamin B6 binding IEA


Pathways (from Reactome)
Pathway description
Metabolism of ingested SeMet, Sec, MeSec into H2Se


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001463 abnormal spatial learning "defects in the abilibity to navigate using behavioraly meaningful locations" [CFG:Center for Functional Genomics , Northwestern University]
Show

Allelic Composition: KitW-sh/KitW-sh
Genetic Background: involves: 101/H * C3H/HeH * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr