ENSMUSG00000026384
Mus musculus domain Ptpn4 protein phosphatase ferm superfamily activity protein-tyrosine tyrosine dephosphorylation membrane pdz ph-like site plasma binding ptp type specific phosphatases ezrin radixin moesin-like catalytic non-receptor type- - acyl-coa-binding adjacent fa active
Features Gene ID: ENSMUSG00000026384 Biological name :Ptpn4 Synonyms : Ptpn4 / Q9WU22 / Tyrosine-protein phosphatase non-receptor type 4 Possible biological names infered from orthology : P29074 / protein tyrosine phosphatase, non-receptor type 4 Species: Mus musculus Chr. number: 1 Strand: -1 Band: E2.3 Gene start: 119652467 Gene end: 119837613 Corresponding Affymetrix probe sets: 10357191 (MoGene1.0st) 1421330_at (Mouse Genome 430 2.0 Array) 1434671_at (Mouse Genome 430 2.0 Array) Cross references: Ensembl peptide - ENSMUSP00000129180 Ensembl peptide - ENSMUSP00000130841 Ensembl peptide - ENSMUSP00000130808 Ensembl peptide - ENSMUSP00000130299 Ensembl peptide - ENSMUSP00000129521 Ensembl peptide - ENSMUSP00000067614 Ensembl peptide - ENSMUSP00000126130 Ensembl peptide - ENSMUSP00000126216 Ensembl peptide - ENSMUSP00000127713 Ensembl peptide - ENSMUSP00000127998 NCBI entrez gene - 19258
See in Manteia .
MGI - MGI:1099792 RefSeq - XM_011247943 RefSeq - NM_019933 RefSeq - XM_006529253 RefSeq - XM_006529254 RefSeq - XM_006529255 RefSeq - XM_006529256 RefSeq Peptide - NP_064317 swissprot - F7CWQ9 swissprot - E9Q210 swissprot - E9QA59 swissprot - Q9WU22 swissprot - E9Q0S8 swissprot - E9PUU9 swissprot - F6PWT7 swissprot - F6U7Q0 swissprot - F6ZWR8 swissprot - F6ZHZ9 Ensembl - ENSMUSG00000026384
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )
Paralog prediction (from Ensembl ) Ptpn3 / A2ALK8 / protein tyrosine phosphatase, non-receptor type 3 / P26045* ENSMUSG00000038764 51 Q9WV92 / Epb41l3 / Band 4.1-like protein 3 Band 4.1-like protein 3, N-terminally processed / Q9Y2J2* / erythrocyte membrane protein band 4.1 like 3* ENSMUSG00000024044 23 Epb41l1 / band 4.1-like protein 1 isoform d / Q9H4G0* / erythrocyte membrane protein band 4.1 like 1* ENSMUSG00000027624 23 O70318 / Epb41l2 / Mus musculus erythrocyte membrane protein band 4.1 like 2 (Epb41l2), transcript variant 3, mRNA. / O43491* / erythrocyte membrane protein band 4.1 like 2* ENSMUSG00000019978 22 Epb41 / P48193 / erythrocyte membrane protein band 4.1 / P11171* ENSMUSG00000028906 22 Q8BGS1 / Epb41l5 / Band 4.1-like protein 5 / Q9HCM4* / erythrocyte membrane protein band 4.1 like 5* ENSMUSG00000026383 19 P52963 / Epb41l4a / Band 4.1-like protein 4A / Q9HCS5* / erythrocyte membrane protein band 4.1 like 4A* ENSMUSG00000024376 18 Q9JMC8 / Epb41l4b / Band 4.1-like protein 4B / Q9H329* / erythrocyte membrane protein band 4.1 like 4B* ENSMUSG00000028434 16 Frmd3 / Q8BHD4 / FERM domain-containing protein 3 / A2A2Y4* / FERM domain containing 3* ENSMUSG00000049122 15 Frmd5 / Q6P5H6 / FERM domain-containing protein 5 / Q7Z6J6* / FERM domain containing 5* ENSMUSG00000027238 14
Protein motifs (from Interpro )
Gene Ontology (GO ) nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic process cellular metabolic process primary metabolic process organic substance metabolic process nitrogen compound metabolic processnitrogen compound metabolic process cellular metabolic processcellular metabolic process primary metabolic processprimary metabolic process organic substance metabolic processorganic substance metabolic process catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a protein hydrolase activity protein binding catalytic activity, acting on a proteincatalytic activity, acting on a protein hydrolase activityhydrolase activity protein bindingprotein binding cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cell organelle membrane cellcell organelleorganelle membranemembrane
Pathways (from Reactome )
Phenotype (from MGI , Zfin or HPO ) behavior/neurological phenotype nervous system phenotype behavior/neurological phenotype nervous system phenotype behavior/neurological phenotype nervous system phenotype behavior/neurological phenotype nervous system phenotype behavior/neurological phenotype nervous system phenotype behavior/neurological phenotype nervous system phenotype behavior/neurological phenotype nervous system phenotype behavior/neurological phenotype nervous system phenotype behavior/neurological phenotype nervous system phenotype behavior/neurological phenotype nervous system phenotype behavior/neurological phenotypebehavior/neurological phenotype nervous system phenotypenervous system phenotype MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: PhexHyp /Phex+ Genetic Background: B6.Cg-PhexHyp /J
MP:0001475 reduced long term depression "less than the normal, persistent activity-dependent decrease in synaptic efficacy between neurons, often following slow, weak stimulation of CA1 neurons" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science:ISBN 0-8385-8034-3]
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Allelic Composition: PhexHyp /Phex+ Genetic Background: B6.Cg-PhexHyp /J
MP:0002807 abnormal eye blink conditioning behavior "defects in the ability of an animal to learn to blink in anticipation of an aversive stimulus (e.g., an airpuff to the eyelid) following repeated pairings with a neutral stimulus (e.g., a tone); such learning is only adaptive if the animal is able to learn the precise timing between the conditioned and unconditioned stimuli " [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: PhexHyp /Phex+ Genetic Background: B6.Cg-PhexHyp /J
Interacting proteins (from Reactome )No match
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