ENSMUSG00000026708


Mus musculus

Features
Gene ID: ENSMUSG00000026708
  
Biological name :Cenpl
  
Synonyms : Cenpl / Centromere protein L / Q3U3S3
  
Possible biological names infered from orthology : Q8N0S6
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H2.1
Gene start: 161070713
Gene end: 161086724
  
Corresponding Affymetrix probe sets: 10351047 (MoGene1.0st)   1429326_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142254
Ensembl peptide - ENSMUSP00000028035
Ensembl peptide - ENSMUSP00000107245
Ensembl peptide - ENSMUSP00000107247
Ensembl peptide - ENSMUSP00000138058
Ensembl peptide - ENSMUSP00000141326
Ensembl peptide - ENSMUSP00000141428
Ensembl peptide - ENSMUSP00000141872
NCBI entrez gene - 70454     See in Manteia.
MGI - MGI:1917704
RefSeq - NM_001159930
RefSeq Peptide - NP_001153402
swissprot - M0QWX6
swissprot - Q05CX4
swissprot - Q14A61
swissprot - Q3U3S3
Ensembl - ENSMUSG00000026708
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cenplENSDARG00000038802Danio rerio
 CENPLENSGALG00000038411Gallus gallus
 CENPLENSG00000120334Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR025204  Centromere subunit L


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000562 polydactyly "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0010101 increased sacral vertebrae number "increase of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Cdkn1atm1.1(KOMP)Vlcg/Cdkn1atm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Cdkn1atm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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