ENSMUSG00000026869


Mus musculus

Features
Gene ID: ENSMUSG00000026869
  
Biological name :Psmd5
  
Synonyms : 26S proteasome non-ATPase regulatory subunit 5 / Psmd5 / Q8BJY1
  
Possible biological names infered from orthology : proteasome 26S subunit, non-ATPase 5 / Q16401
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: B
Gene start: 34849734
Gene end: 34874968
  
Corresponding Affymetrix probe sets: 10481920 (MoGene1.0st)   1423234_at (Mouse Genome 430 2.0 Array)   1443890_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028225
Ensembl peptide - ENSMUSP00000116880
NCBI entrez gene - 66998     See in Manteia.
MGI - MGI:1914248
RefSeq - XM_017319212
RefSeq - NM_080554
RefSeq - XM_006498238
RefSeq Peptide - NP_542121
swissprot - Q8BJY1
swissprot - F7BA91
Ensembl - ENSMUSG00000026869
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 psmd5ENSDARG00000059046Danio rerio
 PSMD5ENSGALG00000001637Gallus gallus
 PSMD5ENSG00000095261Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR014756  Immunoglobulin E-set
 IPR016024  Armadillo-type fold
 IPR019538  26S proteasome non-ATPase regulatory subunit 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043248 proteasome assembly IEA
 biological_processGO:0070682 proteasome regulatory particle assembly IBA
 cellular_componentGO:0008540 proteasome regulatory particle, base subcomplex IEA
 cellular_componentGO:0022624 proteasome accessory complex IDA
 molecular_functionGO:0005488 binding IEA


Pathways (from Reactome)
Pathway description
AUF1 (hnRNP D0) binds and destabilizes mRNA
ABC-family proteins mediated transport
Antigen processing: Ubiquitination & Proteasome degradation
Activation of NF-kappaB in B cells
Asymmetric localization of PCP proteins
CDK-mediated phosphorylation and removal of Cdc6
CLEC7A (Dectin-1) signaling
Degradation of DVL
Degradation of GLI1 by the proteasome
Cross-presentation of soluble exogenous antigens (endosomes)
Degradation of beta-catenin by the destruction complex
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
Downstream TCR signaling
GLI3 is processed to GLI3R by the proteasome
Hedgehog on state
Interleukin-1 signaling
MAPK6/MAPK4 signaling
Neddylation
Orc1 removal from chromatin
Regulation of PTEN stability and activity
Regulation of ornithine decarboxylase (ODC)
Regulation of RUNX2 expression and activity
Regulation of RAS by GAPs
SCF(Skp2)-mediated degradation of p27/p21
Regulation of RUNX3 expression and activity
TNFR2 non-canonical NF-kB pathway
Ub-specific processing proteases
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
UCH proteinases
Ubiquitin-dependent degradation of Cyclin D1
Separation of Sister Chromatids
NIK-->noncanonical NF-kB signaling
APC/C:Cdc20 mediated degradation of Securin
Autodegradation of the E3 ubiquitin ligase COP1
SCF-beta-TrCP mediated degradation of Emi1
Autodegradation of Cdh1 by Cdh1:APC/C
CDT1 association with the CDC6:ORC:origin complex
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
FCERI mediated NF-kB activation
Hedgehog ligand biogenesis
The role of GTSE1 in G2/M progression after G2 checkpoint
G2/M Checkpoints
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Dectin-1 mediated noncanonical NF-kB signaling
Degradation of AXIN
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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